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术中光学相干断层扫描(OCT)联合可折叠人工玻璃体球囊(FCVB)植入术在复杂视网膜脱离伴硅油依赖眼中的疗效

The efficacy of intraoperative OCT combined with foldable artificial vitreous balloon (FCVB) implantation in eyes with complex retinal detachment and silicone oil dependence.

作者信息

Huang Mingxuan, Lu Haomin, Sun Minghao, Lv Jin, Yu Haotian, Jiang Bo, Sun Dawei

机构信息

Department of ophthalmology, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang District, Harbin, 150086, China.

出版信息

BMC Ophthalmol. 2025 Jul 31;25(1):441. doi: 10.1186/s12886-025-04197-3.

Abstract

OBJECTIVE

To evaluate implantation of a foldable capsular vitreous body (FCVB) in combination with intraoperative optical coherence tomography (I-OCT) for the treatment of complex retinal detachment and silicone oil-dependent eyes.

METHODS

This retrospective study included 10 patients (10 eyes) who underwent third-generation FCVB implantation at the Second Affiliated Hospital of Harbin Medical University. Clinical data, including best-corrected visual acuity (BCVA) and intraocular pressure (IOP), were collected preoperatively and at 1 week, 1 month, 3 months, and 6 months postoperatively. During surgery, I-OCT was employed to dynamically monitor the silicone oil injection volume (ranging from 2.1 to 4.5 mL, based on preoperative axial length and 3D ocular reconstructions), ensuring the posterior FCVB wall adhered to the macular retina with a gap of < 100 μm, and maintaining > 500 μm clearance from the anterior capsule to the iris to preserve the posterior chamber space. Pre-, intra-, and postoperative OCT images of the anterior and posterior segments were compared.

RESULTS

All surgeries were completed successfully without intraoperative complications. I-OCT enabled real-time optimization of silicone oil volume, resulting in tight FCVB-retina adherence (< 50 μm) in 8 of 10 eyes. In 2 trauma-related cases with retinal defects, FCVB adhered directly to the sclera. BCVA showed no significant improvement at 6 months. Two cases experienced elevated IOP at 1 week post-op (34 mmHg and 22 mmHg), both of which normalized after treatment. IOP remained stable (15-22 mmHg) in all eyes at final follow-up.

CONCLUSION

I-OCT provided real-time quantitative feedback that allowed precise control of silicone oil injection, ensured optimal positioning of the FCVB, and reduced postoperative complications. Key intraoperative parameters included (1) real-time silicone oil volume titration, (2) gap measurement between FCVB and retina (< 100 μm), and (3) anterior chamber space evaluation (> 500 μm). The use of I-OCT significantly enhanced surgical precision and enabled individualized treatment planning.

摘要

目的

评估可折叠囊袋玻璃体(FCVB)植入联合术中光学相干断层扫描(I-OCT)治疗复杂视网膜脱离和硅油依赖眼的效果。

方法

这项回顾性研究纳入了在哈尔滨医科大学附属第二医院接受第三代FCVB植入术的10例患者(10只眼)。收集术前以及术后1周、1个月、3个月和6个月的临床数据,包括最佳矫正视力(BCVA)和眼压(IOP)。手术过程中,采用I-OCT动态监测硅油注入量(根据术前眼轴长度和三维眼部重建,注入量为2.1至4.5 mL),确保FCVB后壁与黄斑视网膜紧密贴合,间隙<100μm,并保持前囊与虹膜之间>500μm的间隙以保留后房空间。比较眼前段和眼后段术前、术中和术后的OCT图像。

结果

所有手术均成功完成,无术中并发症。I-OCT能够实时优化硅油注入量,10只眼中有8只实现了FCVB与视网膜紧密贴合(<50μm)。在2例与外伤相关的视网膜缺损病例中,FCVB直接贴附于巩膜。6个月时BCVA无显著改善。2例患者术后1周眼压升高(分别为34 mmHg和22 mmHg),经治疗后均恢复正常。末次随访时所有眼的眼压均保持稳定(15 - 22 mmHg)。

结论

I-OCT提供实时定量反馈,可精确控制硅油注入,确保FCVB最佳定位,并减少术后并发症。关键术中参数包括:(1)实时硅油注入量滴定;(2)FCVB与视网膜之间的间隙测量(<100μm);(3)前房空间评估(>500μm)。I-OCT的使用显著提高了手术精度,并实现了个体化治疗方案的制定。

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