Uchiyama Y, Murakami G, Ohno Y
Cell Tissue Res. 1985;242(2):457-60. doi: 10.1007/BF00214563.
Axon profiles in thyroid glands obtained from adult male Wistar rats were studied electron-microscopically, using common and serial thin sections. Bouton profiles of nerve fibers, resembling the terminal or en passant type, often appeared closely associated with vascular smooth muscle cells via basement membranes. These structures are probably adrenergic, since they contained mainly small-core vesicles (mean diameter: 41.2 nm), in addition to a few large-core (mean diameter: 88.4 nm) and flattened vesicles. Nerve fibers containing microtubules and sometimes mitochondria and vesicles were seen lying between basement membranes and follicular cells. The incidence of nerve fiber contacts on profiles of follicular cells was 0.0177 +/- 0.0092 (S.D.). Using serial sections, follicles were seen to have up to two nerve endings, separated from the plasma membranes of the follicular cells by a gap of 22 nm. They contained mainly flattened vesicles and several large-core vesicles (mean diameter: 95.1 nm). Small-core vesicles were rarely seen in these nerve endings. Furthermore, subsurface cistern-like rough endoplasmic reticulum was found immediately under the plasma membranes of follicular cells facing membranes of nerve endings. These results suggest that the nerve fibers in contact with follicular cells are different from the adrenergic type.
利用普通薄切片和连续薄切片，对成年雄性Wistar大鼠甲状腺中的轴突轮廓进行了电子显微镜研究。神经纤维的终扣轮廓，类似终末型或中途型，常通过基底膜与血管平滑肌细胞紧密相连。这些结构可能是肾上腺素能的，因为它们除了含有一些大核心囊泡（平均直径：88.4纳米）和平扁囊泡外，主要含有小核心囊泡（平均直径：41.2纳米）。含有微管、有时还有线粒体和囊泡的神经纤维见于基底膜和滤泡细胞之间。滤泡细胞轮廓上神经纤维接触的发生率为0.0177±0.0092（标准差）。利用连续切片观察到，滤泡最多有两个神经末梢，与滤泡细胞的质膜相隔22纳米的间隙。它们主要含有扁平囊泡和几个大核心囊泡（平均直径：95.1纳米）。在这些神经末梢中很少见到小核心囊泡。此外，在滤泡细胞面向神经末梢膜的质膜下方立即发现了表面下池样粗面内质网。这些结果表明，与滤泡细胞接触的神经纤维不同于肾上腺素能类型。
