Effect of Neprilysin Inhibition on Plasma Proteins in Heart Failure With Mildly Reduced or Preserved Ejection Fraction.
作者信息
Zhang Luqing, Claggett Brian L, Marti-Castellote Pablo M, Yates Denise, Mendelson Michael M, McMurray John J V, Zile Michael R, Chutkow William, Solomon Scott D, Cunningham Jonathan W
机构信息
Novartis Institute for Biomedical Research, Cambridge, Massachusetts, USA.
Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
出版信息
JACC Heart Fail. 2025 Jun 17;13(8):102502. doi: 10.1016/j.jchf.2025.04.012.
Abstract
摘要
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Proteomic Biomarkers of Sacubitril/Valsartan Treatment Response in Heart Failure With Preserved Ejection Fraction: Molecular Insights Into Sex Differences.沙库巴曲缬沙坦治疗射血分数保留的心力衰竭反应的蛋白质组学生物标志物：性别差异的分子见解
Circ Heart Fail. 2022 Sep;15(9):e009629. doi: 10.1161/CIRCHEARTFAILURE.122.009629. Epub 2022 Jun 3.
2
Atrial Natriuretic Peptide and Treatment With Sacubitril/Valsartan in Heart Failure With Reduced Ejection Fraction.利钠肽与沙库巴曲缬沙坦治疗射血分数降低的心力衰竭。
JACC Heart Fail. 2021 Feb;9(2):127-136. doi: 10.1016/j.jchf.2020.09.013. Epub 2020 Nov 11.
3
Effect of Sacubitril/Valsartan on Biomarkers of Extracellular Matrix Regulation in Patients With HFpEF.沙库巴曲缬沙坦对 HFpEF 患者细胞外基质调节生物标志物的影响。
J Am Coll Cardiol. 2020 Aug 4;76(5):503-514. doi: 10.1016/j.jacc.2020.05.072.
4
Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.血管紧张素-脑啡肽酶抑制剂在射血分数保留的心力衰竭中的应用。
N Engl J Med. 2019 Oct 24;381(17):1609-1620. doi: 10.1056/NEJMoa1908655. Epub 2019 Sep 1.
5
The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial.血管紧张素受体脑啡肽酶抑制剂 LCZ696 治疗射血分数保留的心力衰竭的 II 期双盲随机对照试验。
Lancet. 2012 Oct 20;380(9851):1387-95. doi: 10.1016/S0140-6736(12)61227-6. Epub 2012 Aug 26.
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