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一项前瞻性随机临床试验,旨在比较尿道下裂修复术后两种敷料技术在伤口愈合、美容和功能结果以及术后不良事件方面的差异。

A prospective randomized clinical trial to evaluate wound healing, cosmetic and functional results as well as postoperative adverse events comparing two types of dressing technique after hypospadias repair.

作者信息

Lawo Kristin, Feller Dominique, Klein Birgit S, Holland-Cunz Stefan G, Frech-Dörfler Martina

机构信息

Department of Pediatric Surgery, University Children's Hospital Basel, Basel, Switzerland.

University of Basel, Basel, Switzerland.

出版信息

Pediatr Surg Int. 2025 Jun 18;41(1):176. doi: 10.1007/s00383-025-06063-1.

DOI:10.1007/s00383-025-06063-1
PMID:40533580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12177010/
Abstract

BACKGROUND

Dressing technique after hypospadias repair is one of the most controversially discussed subjects in the aftercare. Although current literature presents an enormous number of publications regarding postoperative dressing techniques, there is still no consent on how and if to perform postoperative dressing. The aim of this study is to evaluate two techniques (circular film dressing vs. silver pad covered with film dressing) frequently used in clinical routine after hypospadias surgery.

METHODS

Primary outcomes of this prospective randomized clinical trial were wound healing using Southampton Wound Assessment Scale (SWAS) and cosmetic and functional result using Hypospadias Objective Penile Evaluation (HOPE)-Score. Secondary outcomes were postoperative adverse events.

RESULTS

44 patients were included and randomized into two groups (n = 24 for film dressing vs. n = 20 silver pad dressing). Concerning the primary outcomes, no significant difference in SWAS and HOPE score could be shown. Secondary outcomes showed a statistically significant higher rate of wound dehiscence in the silver pad group and no other statistically significant differences.

CONCLUSIONS

This study could not show superiority of one dressing regarding wound healing or functional and cosmetic result and thereby strengthens the assumption that the individual dressing technique does not play a crucial role in the postoperative outcome.

摘要

背景

尿道下裂修复术后的包扎技术是术后护理中讨论最具争议的话题之一。尽管当前文献中有大量关于术后包扎技术的出版物,但对于如何进行以及是否进行术后包扎仍未达成共识。本研究的目的是评估尿道下裂手术后临床常规常用的两种技术(圆形薄膜敷料与覆盖薄膜敷料的银垫)。

方法

这项前瞻性随机临床试验的主要结局是使用南安普顿伤口评估量表(SWAS)评估伤口愈合情况,以及使用尿道下裂客观阴茎评估(HOPE)评分评估外观和功能结果。次要结局是术后不良事件。

结果

纳入44例患者并随机分为两组(薄膜敷料组n = 24,银垫敷料组n = 20)。关于主要结局,SWAS和HOPE评分未显示出显著差异。次要结局显示银垫组伤口裂开率在统计学上显著更高,且无其他统计学显著差异。

结论

本研究未能显示出一种敷料在伤口愈合或功能及外观结果方面的优越性,从而强化了这样一种假设,即个体包扎技术在术后结局中并不起关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b5/12177010/9183ed3b4ade/383_2025_6063_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b5/12177010/66e06a4c0a00/383_2025_6063_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b5/12177010/9183ed3b4ade/383_2025_6063_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b5/12177010/66e06a4c0a00/383_2025_6063_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b5/12177010/9183ed3b4ade/383_2025_6063_Fig2_HTML.jpg

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本文引用的文献

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The Role of Postoperative Dressing in Hypospadias Surgery: A Systematic Review and Meta-analysis of the Pediatric Literature.术后敷料在尿道下裂手术中的作用:儿科文献的系统评价和荟萃分析。
Eur J Pediatr Surg. 2023 Dec;33(6):441-453. doi: 10.1055/a-2048-7486. Epub 2023 Mar 7.
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A prospective clinical pilot study comparing two post-operative dressings in the treatment of surgical incisions in volunteers.一项比较两种术后敷料对志愿者手术切口治疗效果的前瞻性临床试点研究。
J Wound Care. 2022 Sep 1;31(Sup9):S28-S32. doi: 10.12968/jowc.2022.31.Sup9.S28.
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Tissue glue-based dressings following hypospadias repair: A game-changer or a useless gimmick!
尿道下裂修复术后基于组织胶水的敷料:变革之举还是无用噱头!
J Pediatr Urol. 2021 Oct;17(5):679-680. doi: 10.1016/j.jpurol.2021.08.014. Epub 2021 Aug 18.
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Dressing or Not after Tubularized Incised Plate Urethroplasty.管状切开板尿道成形术后是否需要包扎。
Urol Int. 2021;105(11-12):1029-1033. doi: 10.1159/000516682. Epub 2021 Jun 30.
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Evaluation of a New Tubular Finger Oxygen-Enriched Oil Inside-Coated Dressing Device in Pediatric Patients Undergoing Distal Hypospadias Repair: A Prospective Randomized Clinical Trial Part II.新型管状手指富氧油内涂层敷料装置在小儿远端尿道下裂修复术中的应用评估:一项前瞻性随机临床试验 第二部分
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The Cock-up Splint: A Novel Malleable, Rigid, and Durable Dressing Construct for the Post-hypospadias Repair.阴茎头向上弯曲夹板:一种用于尿道下裂修复术后的新型可塑、刚性且耐用的敷料结构。
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A Comparative Analysis of Surgical Wound Infection Methods: Predictive Values of the CDC, ASEPSIS, and Southampton Scoring Systems in Evaluating Breast Reconstruction Surgical Site Infections.手术伤口感染方法的比较分析:疾控中心、无菌操作和南安普顿评分系统在评估乳房重建手术部位感染中的预测价值
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