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心肌梗死后心室双破裂:一例报告及文献综述

Ventricular double rupture following myocardial infarction: a case report and literature review.

作者信息

Calderon-Miranda Camilo Andres, Vesga-Reyes Carlos Enrique, Olaya Pastor, Reyes-Cardona Maria Juliana, Sanchez-Blanco Jairo, Zambrano-Franco Jorge Alexander, Cruz-Suarez Gustavo Adolfo, Peña-Gonzalez Alvaro Diego

机构信息

Departamento de Cardiología, Fundación Valle del Lili, Carrera 98 No. 18 - 49, Cali, 760032, Colombia.

Facultad de Ciencias de la Salud, Universidad Icesi, Calle 18 No. 122-135, Cali, 760031, Colombia.

出版信息

Int J Emerg Med. 2025 Jun 18;18(1):105. doi: 10.1186/s12245-025-00907-2.

DOI:10.1186/s12245-025-00907-2
PMID:40533731
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12175461/
Abstract

BACKGROUND

The frequency of mechanical complications related to transmural myocardial infarction (MI) has decreased due to the widespread implementation of reperfusion therapies. However, mortality related to these complications remains high, requiring prompt intervention by a Heart Team. Ventricular double rupture (VDR) is a particularly rare and fatal MI complication.

CASE PRESENTATION

A 58-year-old female patient presenting with 3 days of chest pain was diagnosed with ST-elevation MI. She underwent primary percutaneous coronary intervention of the left anterior descending artery. Transthoracic echocardiogram revealed an apical ventricular septum rupture and a mild pericardial effusion suggestive of free wall rupture. Emergent surgical repair included ventricular septal defect closure with a heterologous pericardial patch and repair of the free wall rupture with Dacron patch placement. Perioperative intraaortic balloon pump support was utilized. The patient had a favorable clinical course and was asymptomatic at her cardiology follow-up.

CONCLUSIONS

VDR is the combination of two types of mechanical complications of MI. High clinical suspicion is necessary in hemodynamically unstable patients and those with risk factors for myocardial rupture, warranting echocardiographic evaluation for its diagnosis and characterization. Treatment of VDR is primarily surgical and may involve mechanical circulatory support (MCS). Despite advances in reperfusion therapies and surgical techniques, the prognosis of VDR remains poor. Our patient had a favorable outcome highlighting the importance of a multidisciplinary approach.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1186/s12245-025-00907-2.

摘要

背景

由于再灌注治疗的广泛应用,与透壁性心肌梗死(MI)相关的机械性并发症的发生率有所下降。然而,这些并发症相关的死亡率仍然很高,需要心脏团队及时干预。心室双破裂(VDR)是一种极其罕见且致命的MI并发症。

病例介绍

一名58岁女性患者,胸痛3天,被诊断为ST段抬高型MI。她接受了左前降支的急诊经皮冠状动脉介入治疗。经胸超声心动图显示心尖室间隔破裂和少量心包积液,提示游离壁破裂。急诊手术修复包括用异体心包补片封闭室间隔缺损,并用涤纶补片修复游离壁破裂。术中使用了主动脉内球囊泵支持。患者临床过程顺利,心脏科随访时无症状。

结论

VDR是MI两种机械性并发症的组合。对于血流动力学不稳定的患者以及有心肌破裂危险因素的患者,必须高度怀疑,需要进行超声心动图评估以明确诊断和特征。VDR的治疗主要是手术治疗,可能需要机械循环支持(MCS)。尽管再灌注治疗和手术技术取得了进展,但VDR的预后仍然很差。我们的患者取得了良好的结果,突出了多学科方法的重要性。

补充信息

在线版本包含可在10.1186/s12245-025-00907-2获取的补充材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/9d86a84c8876/12245_2025_907_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/5ab61b5669eb/12245_2025_907_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/557602180067/12245_2025_907_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/21c007b88672/12245_2025_907_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/e21441d91881/12245_2025_907_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/ae725be7d2cc/12245_2025_907_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/9d86a84c8876/12245_2025_907_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/5ab61b5669eb/12245_2025_907_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/557602180067/12245_2025_907_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/21c007b88672/12245_2025_907_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/e21441d91881/12245_2025_907_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/ae725be7d2cc/12245_2025_907_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/597e/12175461/9d86a84c8876/12245_2025_907_Fig6_HTML.jpg

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本文引用的文献

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Temporary mechanical circulatory support in infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials with 6-month follow-up.梗死相关心原性休克的临时机械循环支持:6 个月随访的随机试验的个体患者数据荟萃分析。
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急性心肌梗死的机械并发症:美国心脏协会的科学声明。
Circulation. 2021 Jul 13;144(2):e16-e35. doi: 10.1161/CIR.0000000000000985. Epub 2021 Jun 15.
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Mechanical Complications of Acute Myocardial Infarction: A Review.急性心肌梗死的机械并发症:综述
JAMA Cardiol. 2021 Mar 1;6(3):341-349. doi: 10.1001/jamacardio.2020.3690.
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Survival after left ventricular free wall rupture following acute myocardial infarction by conservative treatment.急性心肌梗死后采用保守治疗存活的左心室游离壁破裂
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