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药物涂层球囊用于年轻ST段抬高型心肌梗死患者:一种可行的治疗选择?

Drug Coated Balloon in Young Patients With ST-Elevation Myocardial Infarction: A Viable Treatment Option?

作者信息

Vukadinović Davor, Kulenthiran Saarraaken, Mahfoud Felix, Scheller Bruno

机构信息

Innere Medizin III-Kardiologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg, Germany.

Department of Cardiology, University Heart Center, University Hospital Basel, Basel, Switzerland.

出版信息

Catheter Cardiovasc Interv. 2025 Aug;106(2):1367-1370. doi: 10.1002/ccd.31699. Epub 2025 Jun 18.

Abstract

This clinical case highlights the safety and feasibility of drug coated balloon (DCB) angioplasty in a very young patients presenting with STEMI (ST-Elevation Myocardial Infarction) to avoid long-term complications associated with stent implantation, which still amount to 1%-2%. We successfully treated a 25 years old patient with occluded right coronary artery (RCA) with DCB after careful lesion preparation. Moreover, in a control angiogram 7 weeks later the RCA was patent with substantial lumen enlargement of 0.4 mm (RAO projection) to almost 2 mm (LAO projection) in a very short period of time. DCB angioplasty offers a viable alternative to stent implantation in young patients, avoiding the complications associated with permanent metallic implants while promoting vascular remodeling. While we acknowledge that more evidence is needed to optimize patient selection and confirm the long-term benefits of DCB in ACS, this case highlights its efficacy and safety in terms of an individualized treatment strategy.

摘要

该临床病例凸显了药物涂层球囊(DCB)血管成形术在极年轻的ST段抬高型心肌梗死(STEMI)患者中的安全性和可行性,可避免与支架植入相关的长期并发症,此类并发症仍达1%-2%。我们在仔细进行病变预处理后,成功地用DCB治疗了一名25岁右冠状动脉(RCA)闭塞的患者。此外,在7周后的对照血管造影中,RCA保持通畅,在很短时间内管腔显著扩大,从0.4毫米(右前斜位投影)增至近2毫米(左前斜位投影)。DCB血管成形术为年轻患者提供了一种可行的支架植入替代方案,避免了与永久性金属植入物相关的并发症,同时促进血管重塑。虽然我们承认需要更多证据来优化患者选择并确认DCB在急性冠状动脉综合征(ACS)中的长期益处,但该病例凸显了其在个体化治疗策略方面的有效性和安全性。

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