Yilmaz Orhan, Doiron Philip, Evans Robyn
College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Division of Dermatology, Department of Medicine, Faculty of Medicine, University of Toronto School of Medicine, ON, Canada.
SAGE Open Med Case Rep. 2025 Jun 16;13:2050313X251350372. doi: 10.1177/2050313X251350372. eCollection 2025.
Pyoderma gangrenosum is a rare, ulcerative skin condition with complex diagnostic and therapeutic challenges, particularly in cases without associated systemic conditions. We present the case of a 71-year-old female with a chronic, non-healing ulcer, initially unresponsive to conventional topical treatments. After a thorough evaluation and biopsy, a diagnosis of pyoderma gangrenosum was made. Treatment efforts included both intralesional and topical therapies, with varying responses observed. This case highlights the challenges in diagnosing and managing pyoderma gangrenosum, emphasizing the need for individualized care and a multidisciplinary approach to treat chronic, non-healing ulcers.
坏疽性脓皮病是一种罕见的溃疡性皮肤病，诊断和治疗面临复杂挑战，尤其是在无相关全身性疾病的病例中。我们报告一例71岁女性患者，患有慢性不愈合溃疡，最初对传统局部治疗无反应。经过全面评估和活检，诊断为坏疽性脓皮病。治疗措施包括病灶内注射和局部治疗，观察到不同的反应。该病例突出了坏疽性脓皮病诊断和管理中的挑战，强调了针对慢性不愈合溃疡进行个体化护理和多学科治疗方法的必要性。
