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后巩膜缩短联合玻璃体腔内注射CF治疗高度近视合并黄斑裂孔性视网膜脱离的疗效

Efficacy of combining posterior scleral contraction and intravitreal CF injection in high myopia with macular hole retinal detachment.

作者信息

Chen Si, Ye Jie, Pan Qin-Tuo, Huang Fang, Zheng Lin-Yan, Ye Hui-Fang, Su Yan-Feng, Li Yan, Zhu Shuang-Qian

机构信息

National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.

出版信息

Int J Ophthalmol. 2025 Jun 18;18(6):1077-1084. doi: 10.18240/ijo.2025.06.14. eCollection 2025.

Abstract

AIM

To evaluate the efficacy and safety of combining posterior scleral contraction (PSC) with intravitreal perfluoropropane (CF) injection in high myopia with macular hole retinal detachment (MHRD).

METHODS

A total of 22 participants (22 eyes) with high myopia [axial length (AL)≥26.5 mm] and MHRD who underwent PSC combined with intravitreal CF injection, with at least 6mo of follow-up were retrospectively recruited. Outcome measures included best-corrected visual acuity (BCVA), AL, optical coherence tomography (OCT) findings, and adverse events. Retinal recovery was categorized as type I (macular hole bridging with retinal reattachment) or type II (reattachment without hole bridging).

RESULTS

The mean age of participants was 62.1±8.8y and mean follow-up duration was 9.18±4.21mo. Complete retinal reattachment was observed in 11 eyes (50%) at postoperative day 1, 19 eyes (86.3%) at week 1, and all 22 eyes at month 1. Ten eyes (45.5%) achieved type I recovery and 12 eyes (54.5%) achieved type II. Mean BCVA improved from 1.68±0.84 logMAR before surgery to 1.21±0.65 logMAR after surgery (<0.001), and AL was significantly reduced compared to baseline (29.07±2.05 30.8±2.2 mm; <0.001). No serious complications were reported.

CONCLUSION

PSC combined with intravitreal CF injection is a safe and effective treatment for MHRD in highly myopic eyes, especially for retinal detachment limited within the vascular arcade.

摘要

目的

评估后巩膜收缩(PSC)联合玻璃体腔内注射全氟丙烷(CF)治疗高度近视合并黄斑裂孔性视网膜脱离(MHRD)的疗效和安全性。

方法

回顾性招募了22例(22只眼)高度近视[眼轴长度(AL)≥26.5mm]且患有MHRD并接受PSC联合玻璃体腔内CF注射治疗、随访至少6个月的患者。观察指标包括最佳矫正视力(BCVA)、AL、光学相干断层扫描(OCT)结果及不良事件。视网膜恢复情况分为I型(黄斑裂孔桥接且视网膜复位)或II型(视网膜复位但无裂孔桥接)。

结果

患者的平均年龄为62.1±8.8岁,平均随访时间为9.18±4.21个月。术后第1天,11只眼(50%)实现视网膜完全复位;第1周时,19只眼(86.3%)实现视网膜完全复位;第1个月时,所有22只眼均实现视网膜完全复位。10只眼(45.5%)达到I型恢复,12只眼(54.5%)达到II型恢复。平均BCVA从术前的1.68±0.84 logMAR提高到术后的1.21±0.65 logMAR(P<0.001),与基线相比,AL显著缩短(29.07±2.05对30.8±2.2mm;P<0.001)。未报告严重并发症。

结论

PSC联合玻璃体腔内CF注射治疗高度近视合并MHRD是一种安全有效的方法,尤其适用于局限于血管弓内的视网膜脱离。

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