Chen Si, Ye Jie, Pan Qin-Tuo, Huang Fang, Zheng Lin-Yan, Ye Hui-Fang, Su Yan-Feng, Li Yan, Zhu Shuang-Qian
National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Int J Ophthalmol. 2025 Jun 18;18(6):1077-1084. doi: 10.18240/ijo.2025.06.14. eCollection 2025.
To evaluate the efficacy and safety of combining posterior scleral contraction (PSC) with intravitreal perfluoropropane (CF) injection in high myopia with macular hole retinal detachment (MHRD).
A total of 22 participants (22 eyes) with high myopia [axial length (AL)≥26.5 mm] and MHRD who underwent PSC combined with intravitreal CF injection, with at least 6mo of follow-up were retrospectively recruited. Outcome measures included best-corrected visual acuity (BCVA), AL, optical coherence tomography (OCT) findings, and adverse events. Retinal recovery was categorized as type I (macular hole bridging with retinal reattachment) or type II (reattachment without hole bridging).
The mean age of participants was 62.1±8.8y and mean follow-up duration was 9.18±4.21mo. Complete retinal reattachment was observed in 11 eyes (50%) at postoperative day 1, 19 eyes (86.3%) at week 1, and all 22 eyes at month 1. Ten eyes (45.5%) achieved type I recovery and 12 eyes (54.5%) achieved type II. Mean BCVA improved from 1.68±0.84 logMAR before surgery to 1.21±0.65 logMAR after surgery (<0.001), and AL was significantly reduced compared to baseline (29.07±2.05 30.8±2.2 mm; <0.001). No serious complications were reported.
PSC combined with intravitreal CF injection is a safe and effective treatment for MHRD in highly myopic eyes, especially for retinal detachment limited within the vascular arcade.
评估后巩膜收缩(PSC)联合玻璃体腔内注射全氟丙烷(CF)治疗高度近视合并黄斑裂孔性视网膜脱离(MHRD)的疗效和安全性。
回顾性招募了22例(22只眼)高度近视[眼轴长度(AL)≥26.5mm]且患有MHRD并接受PSC联合玻璃体腔内CF注射治疗、随访至少6个月的患者。观察指标包括最佳矫正视力(BCVA)、AL、光学相干断层扫描(OCT)结果及不良事件。视网膜恢复情况分为I型(黄斑裂孔桥接且视网膜复位)或II型(视网膜复位但无裂孔桥接)。
患者的平均年龄为62.1±8.8岁,平均随访时间为9.18±4.21个月。术后第1天,11只眼(50%)实现视网膜完全复位;第1周时,19只眼(86.3%)实现视网膜完全复位;第1个月时,所有22只眼均实现视网膜完全复位。10只眼(45.5%)达到I型恢复,12只眼(54.5%)达到II型恢复。平均BCVA从术前的1.68±0.84 logMAR提高到术后的1.21±0.65 logMAR(P<0.001),与基线相比,AL显著缩短(29.07±2.05对30.8±2.2mm;P<0.001)。未报告严重并发症。
PSC联合玻璃体腔内CF注射治疗高度近视合并MHRD是一种安全有效的方法,尤其适用于局限于血管弓内的视网膜脱离。