Liu Guotao, Xu Qiong, Zhang Suhua, Zhang Jianyuan
Department of Health Care, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, China.
Department of Neurology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, China.
Front Nutr. 2025 Jun 4;12:1589898. doi: 10.3389/fnut.2025.1589898. eCollection 2025.
This study aimed to investigate the association between A Body Shape Index (ABSI) and cognitive impairment in middle-aged and elderly Chinese adults.
We analyzed baseline data from the 2011 China Health and Retirement Longitudinal Study (CHARLS), including 6,762 participants aged ≥45 years. The modified ABSI of adults in China was calculated using waist circumference (WC), body mass index (BMI), and height. Cognitive function was assessed through episodic memory and cognitive status tests, with impairment defined as a composite score ≤11. Multivariate logistic regression, fitted smoothing curves, and subgroup analysis were employed to evaluate the associations and interactions. Receiver operating characteristic (ROC) curves were used to compare the diagnostic performance of ABSI, BMI, and WC.
After full adjustment, each 0.01-unit ABSI increase conferred a 45.7% higher risk of cognitive impairment (odds ratio [OR] = 1.457). Participants in the highest ABSI quartile had a 48.3% higher risk compared to the lowest quartile ( for trend < 0.001). Dose-response analysis revealed a positive relationship ( < 0.001) between ABSI and cognitive impairment. ABSI demonstrated superior diagnostic accuracy (Area Under the Curve [AUC] = 0.603) compared to BMI (AUC = 0.570) and WC (AUC = 0.548).
Elevated ABSI independently predicts cognitive impairment in Chinese middle-aged and older adults. ABSI demonstrates better diagnostic accuracy compared to BMI and WC. These findings highlight ABSI's utility as a cost-effective anthropometric tool for cognitive risk stratification in aging populations.
本研究旨在探讨中国中老年成年人的身体形态指数（ABSI）与认知障碍之间的关联。
我们分析了2011年中国健康与养老追踪调查（CHARLS）的基线数据，包括6762名年龄≥45岁的参与者。使用腰围（WC）、体重指数（BMI）和身高计算中国成年人的改良ABSI。通过情景记忆和认知状态测试评估认知功能，将认知障碍定义为综合评分≤11。采用多因素逻辑回归、拟合平滑曲线和亚组分析来评估关联和相互作用。使用受试者工作特征（ROC）曲线比较ABSI、BMI和WC的诊断性能。
经过全面调整后，ABSI每增加0.01个单位，认知障碍风险增加45.7%（比值比[OR]=1.457）。与最低四分位数相比，最高ABSI四分位数的参与者风险高48.3%（趋势P<0.001）。剂量反应分析显示ABSI与认知障碍之间存在正相关关系（P<0.001）。与BMI（曲线下面积[AUC]=0.570）和WC（AUC=0.548）相比，ABSI显示出更高的诊断准确性（AUC=0.603）。
升高的ABSI独立预测中国中老年成年人的认知障碍。与BMI和WC相比，ABSI显示出更好的诊断准确性。这些发现突出了ABSI作为一种经济有效的人体测量工具在老年人群认知风险分层中的作用。
