The burgeoning user base and potential negative effects of excessive involvement in gaming, particularly Internet Gaming Disorder (IGD), demand significant attention. While existing research has explored the susceptibility of individuals with IGD to game-related stimuli, the question of why it is challenging for these individuals to disengage from gaming remains under-explored. Drawing parallels with the concept of interruption, we hypothesize that negative emotions triggered during gaming interruptions would drive individuals' craving for the game and compelling them to continue playing, reinforcing the IGD cycle. In this study, 42 male 'League of Legends' players, aged 19 to 29, experienced controlled interruptions every 3 min during gaming and non-gaming control tasks. Our findings demonstrate that interruptions during gaming elicited significantly higher levels of anger and anxiety compared to the control tasks. Further, we found a positive correlation between the severity of IGD symptoms and the intensity of anger and anxiety induced by gaming interruptions. Additionally, our analysis suggests that craving partially mediates the relationship between anger arousal during gaming interruptions and IGD severity. These findings provide new insights into how emotional responses to gaming interruptions contribute to IGD, offering a novel perspective for future research and potential treatment approaches.