Suppr超能文献

外科植入式临时心室辅助泵——“Impella 5.5”。

Surgically implanted temporary ventricular assist pump - "Impella 5.5".

作者信息

Chauhan Akshay, Senzai Mikiko, Vijayapuri Sriram, Kehara Hiromu, Yanagida Roh, Krishan Kewal, Toyoda Yoshiya

机构信息

Department of Cardiovascular Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19004 USA.

出版信息

Indian J Thorac Cardiovasc Surg. 2025 Jul;41(7):906-910. doi: 10.1007/s12055-025-01946-3. Epub 2025 Apr 21.

Abstract

The Impella 5.5 (Abiomed, Danvers, MA, USA) is an advanced left ventricular assist device that provides short-term cardiac support for patients with severe heart failure and cardiogenic shock. Its compact size and catheter-based design facilitate relatively straightforward insertion, offering mechanical support to the left ventricle without significantly increasing afterload-two key advantages. A substantial body of clinical trials and real-world evidence have confirmed its efficacy in enhancing cardiac output and organ perfusion. Notably, its short-term support has been associated with improved patient outcomes in cases of cardiogenic shock. However, the use of Impella is not without risks, including bleeding events, peripheral vascular complications, and hemolysis, underscoring the importance of appropriate patient selection, surgical planning, and meticulous post-insertion management. Future research should focus on long-term outcomes, cost-effectiveness, and continued advancements in technology. This review provides a comprehensive analysis of the Impella device, including its design, clinical applications, surgical strategies, benefits, and indications, as well as the challenges associated with its use. It reassesses its role considering the most recent evidence.

摘要

Impella 5.5(美国马萨诸塞州丹弗斯市的Abiomed公司生产)是一种先进的左心室辅助装置,为严重心力衰竭和心源性休克患者提供短期心脏支持。其紧凑的尺寸和基于导管的设计便于相对直接的插入,在不显著增加后负荷的情况下为左心室提供机械支持——这是两个关键优势。大量的临床试验和实际证据证实了其在增加心输出量和器官灌注方面的疗效。值得注意的是,在治疗心源性休克时,其短期支持与改善患者预后相关。然而,使用Impella并非没有风险,包括出血事件、外周血管并发症和溶血,这凸显了适当的患者选择、手术规划和插入后精心管理的重要性。未来的研究应关注长期结果、成本效益以及技术的持续进步。本综述对Impella装置进行了全面分析,包括其设计、临床应用、手术策略、益处和适应症,以及与使用相关的挑战。它根据最新证据重新评估了其作用。

相似文献

1
Surgically implanted temporary ventricular assist pump - "Impella 5.5".外科植入式临时心室辅助泵——“Impella 5.5”。
Indian J Thorac Cardiovasc Surg. 2025 Jul;41(7):906-910. doi: 10.1007/s12055-025-01946-3. Epub 2025 Apr 21.
4
Clinical management of the Impella 5.5 pump.
J Heart Lung Transplant. 2025 Jun 24. doi: 10.1016/j.healun.2025.06.008.
6
Single-incision sling operations for urinary incontinence in women.女性尿失禁的单切口吊带手术
Cochrane Database Syst Rev. 2017 Jul 26;7(7):CD008709. doi: 10.1002/14651858.CD008709.pub3.

本文引用的文献

6
Single center experience and early outcomes of Impella 5.5.Impella 5.5的单中心经验及早期结果。
Front Cardiovasc Med. 2023 Feb 28;10:1018203. doi: 10.3389/fcvm.2023.1018203. eCollection 2023.
10
ECPella: Concept, Physiology and Clinical Applications.体外循环肺辅助装置:概念、生理学及临床应用
J Cardiothorac Vasc Anesth. 2022 Feb;36(2):557-566. doi: 10.1053/j.jvca.2021.01.056. Epub 2021 Feb 6.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验