氙 - 133实质内注射后的清除：一种估算功能性肝血流量的快速方法。

The clearance of Xenon-133 following its parenchymal injection: a rapid method for estimating functional liver blood-flow.

作者信息

Jenkins S A, Taylor A, Shimirty S K, Johnson J, Baxter J N, Taylor I, Shields R

出版信息

Clin Physiol. 1985 Oct;5(5):433-42. doi: 10.1111/j.1475-097x.1985.tb00774.x.

DOI:10.1111/j.1475-097x.1985.tb00774.x

Abstract

Portal venous flow, total hepatic blood-flow and hepatic artery flow were measured in healthy dogs by electromagnetic flowmetry and a double indicator dilution technique. Functional liver blood-flow was measured by the double indicator dilution technique. Functional hepatic blood-flow did not correlate with portal venous flow, total hepatic blood-flow or hepatic artery flow, measured by either electromagnetic flowmetry or a double indicator dilution technique. There was a good correlation (r = 0.83, P less than 0.001) between functional hepatic blood-flow and liver blood-flow, measured by the clearance of Xenon-133 injected directly into the liver parenchyma. It is concluded that the clearance of Xenon-133, injected directly into the liver parenchyma, is a rapid and simple method for measuring functional hepatic blood-flow.

摘要

采用电磁血流测定法和双指示剂稀释技术，对健康犬的门静脉血流、肝总血流量和肝动脉血流进行了测量。采用双指示剂稀释技术测量功能性肝血流量。通过电磁血流测定法或双指示剂稀释技术测得的功能性肝血流量与门静脉血流、肝总血流量或肝动脉血流均无相关性。通过直接注入肝实质的氙-133清除率测得的功能性肝血流量与肝血流量之间存在良好的相关性（r = 0.83，P < 0.001）。结论是，直接注入肝实质的氙-133清除率是一种快速、简便的测量功能性肝血流量的方法。