Tanaka Tatsuya, Liu Xuan, Shojima Hirotaka, Momozaki Nobuaki, Honda Eiichiro, Matsuno Akira
Department of Neurosurgery, International University of Health and Welfare Narita Hospital, Narita, JPN.
Department of Neurosurgery, Shiroishi Kyoritsu Hospital, Shiroishi, JPN.
Cureus. 2025 May 19;17(5):e84419. doi: 10.7759/cureus.84419. eCollection 2025 May.
Osteoporotic vertebral compression fractures are common in the elderly and frequently lead to pain, spinal deformity, and decreased activities of daily living (ADL). While balloon kyphoplasty (BKP) is known to provide rapid pain relief and improve mobility, it does not prevent the occurrence of subsequent adjacent vertebral fractures, especially before the therapeutic effects of pharmacologic osteoporosis treatments such as teriparatide become apparent. We report the case of an 87-year-old super-aged female patient who experienced a cascade of five adjacent vertebral fractures within four months. After conservative treatment failed, she underwent BKP for L1 and L4, resulting in immediate pain relief. However, new fractures subsequently occurred at Th12, L2, and L3, each requiring further BKP. Early surgical intervention after each fracture successfully restored mobility and preserved independence in ADL. Over a five-year follow-up period, no new fractures were observed, and spinal alignment was maintained. This case highlights the utility of early and repeated BKP as a bridging strategy until the effects of osteoporosis treatment take hold. Timely, minimally invasive interventions can prevent deterioration of spinal alignment and preserve quality of life in super-aged patients with severe osteoporosis.
骨质疏松性椎体压缩骨折在老年人中很常见,常导致疼痛、脊柱畸形和日常生活活动能力(ADL)下降。虽然球囊椎体后凸成形术(BKP)已知能迅速缓解疼痛并改善活动能力,但它并不能预防随后相邻椎体骨折的发生,尤其是在诸如特立帕肽等药物性骨质疏松治疗的疗效显现之前。我们报告了一例87岁的超高龄女性患者,她在四个月内连续发生了五例相邻椎体骨折。保守治疗失败后,她接受了L1和L4椎体的BKP治疗,疼痛立即缓解。然而,随后T12、L2和L3椎体又发生了新的骨折,每例都需要进一步的BKP治疗。每次骨折后早期手术干预成功恢复了活动能力,并保持了ADL的独立性。在五年的随访期内,未观察到新的骨折,脊柱排列得以维持。该病例突出了早期和重复BKP作为一种过渡策略的效用,直至骨质疏松治疗的效果显现。及时的微创干预可以防止脊柱排列恶化,并在患有严重骨质疏松的超高龄患者中保持生活质量。