肾移植患者住院期间的尿路感染：真实病例经验
Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience.
作者信息
Pinchera Biagio, Carrano Rosa, Schettino Elisa, D'Agostino Alessia, Trucillo Emilia, Cuccurullo Federica, Salemi Fabrizio, Piccione Amerigo, Gentile Ivan
机构信息
Section of Infectious Diseases, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples 80131, Italy.
Section of Nephrology, Department of Public Health, University of Naples "Federico II", Naples 80131, Italy.
出版信息
World J Transplant. 2025 Jun 18;15(2):99554. doi: 10.5500/wjt.v15.i2.99554.
BACKGROUND
Urinary tract infections (UTIs) in kidney transplant patients are a challenge.
AIM
To evaluate epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients in a university hospital for UTI.
METHODS
We conducted a retrospective observational study, enrolling all kidney transplant patients hospitalized for UTI, with the objective to evaluate the epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients.
RESULTS
From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection. At the same time, the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection.
CONCLUSION
Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.
背景
肾移植患者的尿路感染是一项挑战。
目的
评估某大学医院肾移植患者尿路感染的流行病学、临床状况、治疗管理及临床结局。
方法
我们进行了一项回顾性观察研究，纳入所有因尿路感染住院的肾移植患者，旨在评估肾移植患者的流行病学、临床状况、治疗管理及临床结局。
结果
根据我们的实际经验，多重耐药菌感染被确认为感染严重进展的一个危险因素。同时，重新评估免疫抑制治疗可能是感染过程中的一项重要治疗策略。
结论
在开始微生物学检查后迅速启动经验性抗生素治疗可能会降低严重感染进展的风险。
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