Zhou Meixi, Zhu Linhong, Lan Hua
The Affiliated Stomatological Hospital, Jiangxi Medical College, Nanchang University, Jiangxi Province Key Laboratory of Oral Biomedicine, Jiangxi Province Clinical Research Center for Oral Diseases Nanchang 330006, Jiangxi, China.
Department of General, Stomatology Hospital, General Hospital of Ningxia Medical University Yinchuan 750004, Ningxia Hui Autonomous Region, China.
Am J Transl Res. 2025 May 15;17(5):3454-3464. doi: 10.62347/RKQX9577. eCollection 2025.
This research compares the effectiveness of three whitening treatments for mild-to-moderate dental fluorosis in the front teeth.
This retrospective study analysis is based on 51 mild-to-moderate dental fluorosis cases. The patients who visited the Dental Hospital of Ningxia Medical University from August 2020 to August 2021 were enrolled as research cases. The patients were classified into three groups according to their treatment plans: Group A (19 cases), Group B (17 cases), and Group C (15 cases). The upper anterior teeth color was assessed immediately after treatment and then at one week, one month, three months, and six months using the VITA Easyshade V shade guide. Tooth sensitivity was evaluated with a visual analog scale (VAS scale).
Three options were applied to treat mild and moderate dental fluorosis. Moderate fluorosis showed higher ΔE and ΔL values but lower Δa and Δb values compared to mild fluorosis, with significant differences noted (P<0.05). In cases of mild dental fluorosis, ΔE and ΔL values from the combination of micro-grinding and home bleaching were significantly higher. Conversely, Δa and Δb values for both micro-grinding with home bleaching and micro-grinding with combined bleaching were significantly lower (P<0.05). In moderate dental fluorosis cases, ΔE and ΔL values were higher for both micro-grinding combined with bleaching and micro-grinding combined with home bleaching. In contrast, Δa and Δb values for micro-grinding combined with bleaching were lower, showing statistically significant differences (P<0.05). The sensitivity of micro-grinding + home bleaching was less than that of micro-grinding + in-office bleaching and micro-grinding + combined bleaching immediately post-op, 1 week after the operation, with statistically significant differences (P<0.05).
All three options achieve sound whitening effects for mild to moderate dental fluorosis in anterior teeth. The whitening effect is more effective in cases of moderate dental fluorosis than in mild cases. Among the three treatment options, microabrasion combined with home bleaching achieves the best whitening effect for mild dental fluorosis and minimizes sensitivity. When considering the three treatment options for moderate dental fluorosis, both microabrasion combined with home bleaching and microabrasion combined with in-office bleaching can yield better whitening effects. However, it is essential to note that the latter option is linked to higher sensitivity.
本研究比较三种美白治疗方法对前牙轻至中度氟斑牙的疗效。
本回顾性研究分析基于51例轻至中度氟斑牙病例。将2020年8月至2021年8月期间到宁夏医科大学口腔医院就诊的患者纳入研究病例。根据治疗方案将患者分为三组：A组（19例）、B组（17例）和C组（15例）。治疗后立即使用VITA Easyshade V比色板评估上前牙颜色，然后在1周、1个月、3个月和6个月时进行评估。使用视觉模拟量表（VAS量表）评估牙齿敏感度。
应用三种方法治疗轻、中度氟斑牙。与轻度氟斑牙相比，中度氟斑牙的ΔE和ΔL值较高，但Δa和Δb值较低，差异有统计学意义（P<0.05）。在轻度氟斑牙病例中，微研磨与家庭漂白联合治疗的ΔE和ΔL值显著更高。相反，微研磨联合家庭漂白和微研磨联合复合漂白的Δa和Δb值均显著更低（P<0.05）。在中度氟斑牙病例中，微研磨联合复合漂白和微研磨联合家庭漂白的ΔE和ΔL值均较高。相比之下，微研磨联合复合漂白的Δa和Δb值较低，差异有统计学意义（P<0.05）。微研磨+家庭漂白术后即刻、术后1周的敏感度低于微研磨+诊室漂白和微研磨+复合漂白，差异有统计学意义（P<0.05）。
三种方法对前牙轻至中度氟斑牙均有良好的美白效果。中度氟斑牙的美白效果比轻度病例更显著。在三种治疗方法中，微研磨联合家庭漂白对轻度氟斑牙的美白效果最佳，且敏感度最低。对于中度氟斑牙的三种治疗方法，微研磨联合家庭漂白和微研磨联合诊室漂白均能产生较好的美白效果。然而，必须注意的是，后一种方法的敏感度较高。
