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1998年至2023年德国冠心病死亡率的时间趋势。

Temporal trends in mortality due to coronary heart disease in Germany from 1998 to 2023.

作者信息

Steppuhn Henriette, Baumert Jens, Rücker Viktoria, Günther Kai, Wengler Annelene, Tetzlaff Fabian, Neuhauser Hannelore

机构信息

Robert Koch Institute, Department for Epidemiology and Health Monitoring, Berlin, Germany.

Institut for Clinical Epidemiology und Biometry, University of Würzburg, Germany.

出版信息

J Health Monit. 2025 Jun 11;10(2):e13178. doi: 10.25646/13178. eCollection 2025 Jun.

Abstract

BACKGROUND

Coronary heart disease (CHD) is the leading cause of death in Germany. Comprehensive analyses of long-term trends in CHD mortality that also distinguish between acute myocardial infarction (AMI) and non-AMI-related chronic CHD are currently lacking.

METHOD

Age-specific and age-standardised CHD mortality rates for the period 1998 - 2023 were calculated based on data from the cause-of-death statistics of the Federal Statistical Office of Germany. Annual percentage changes (APC) and average annual percentage changes (AAPC) were estimated using joinpoint regression analysis.

RESULTS

Between 1998 and 2023, the average annual change in age-standardised CHD mortality rates for women was -3.9 % ((-4.1) - (-3.7)) per year, compared with -3.2 % ((-3.3) - (-3.0)) for men. However, since the 2010s, the downward trend in CHD mortality has flattened, particularly among those aged 60 to 74 years. In the analysis by ICD subgroups, mortality rates for chronic CHD declined less sharply than for AMI over the entire period 1998 - 2023, especially among men.

CONCLUSIONS

The flattening of the CHD mortality trend, particularly among middle-aged adults over the last decade, and the smaller decline in chronic CHD mortality, especially among men, require further exploration in order to identify unmet needs at various levels of prevention for specific life stages. In addition, the influence of the COVID-19 pandemic on CHD mortality trends should be further investigated.

摘要

背景

冠心病(CHD)是德国的主要死因。目前缺乏对冠心病死亡率长期趋势的综合分析,且未区分急性心肌梗死(AMI)和非AMI相关的慢性冠心病。

方法

基于德国联邦统计局死因统计数据,计算了1998年至2023年期间特定年龄和年龄标准化的冠心病死亡率。使用Joinpoint回归分析估计年度百分比变化(APC)和平均年度百分比变化(AAPC)。

结果

1998年至2023年期间,女性年龄标准化冠心病死亡率的年均变化为每年-3.9%((-4.1)-(-3.7)),男性为-3.2%((-3.3)-(-3.0))。然而,自2010年代以来,冠心病死亡率的下降趋势趋于平缓,尤其是在60至74岁的人群中。在按国际疾病分类亚组进行的分析中,1998年至2023年期间,慢性冠心病的死亡率下降幅度小于AMI,尤其是在男性中。

结论

冠心病死亡率趋势趋于平缓,尤其是在过去十年中的中年成年人中,以及慢性冠心病死亡率下降幅度较小,尤其是在男性中,需要进一步探索,以确定在特定生命阶段的各级预防中未满足的需求。此外,应进一步调查COVID-19大流行对冠心病死亡率趋势的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a109/12175194/fd26b1d49631/johm-10-2-03-e13178-g001.jpg

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