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初级保健中抑郁症病例发现研究(开罗研究):英国一项多中心横断面研究

Case-finding for depression in primary care (CAIRO): a multicentre, cross-sectional study in England.

作者信息

Lawton Sarah A, Mallen Christian, Chew-Graham Carolyn, Kingstone Tom, Muller Sara, Lewis Sarah, Bajpai Ram, Helliwell Toby

机构信息

Keele CTU, Keele University, Keele, UK

School of Medicine, Keele University, Keele, UK.

出版信息

BMJ Open. 2025 Jun 19;15(6):e095040. doi: 10.1136/bmjopen-2024-095040.

DOI:10.1136/bmjopen-2024-095040
PMID:40537235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12182143/
Abstract

OBJECTIVES

To examine the number of patients screening positive for depression, while self-completing an automated check-in screen prior to a general practice consultation.

DESIGN

A descriptive cross-sectional study.

SETTING

10 general practices in the West Midlands, England. Recruitment commenced in March 2023 and concluded in June 2023.

PARTICIPANTS

All patients aged 18 years and over, self-completing an automated check-in screen for any general practice prebooked appointment, were invited to participate during a 3-week recruitment period.

PRIMARY AND SECONDARY OUTCOME MEASURES

The number of patients screening positive for depression using the Whooley case finding research questions was the primary outcome measure. Secondary outcome measures included: demographic and (general practice level) deprivation differences in completion responses.

RESULTS

73.5% (n=3666) of patients self-completing an automated check-in screen participated in the CAse-fInding foR depressiOn in primary care (CAIRO) study, (61.1% (n=2239) female, mean age 55.0 years (18-96 years, SD=18.5)).28.3% (n=1039) of participants provided a positive response to at least one of the two Whooley research questions (31.2% female and 23.8% male). Significantly more positive responses were obtained from females, those aged between 35 years and 49 years and those from more deprived practices.

CONCLUSIONS

Over a quarter of CAIRO participants provided a positive response to at least one of the two Whooley questions, suggesting possible unmet need in the population studied. A follow-up study could investigate whether responses provided at the point of check-in are raised and addressed in the subsequent consultation.

摘要

目的

在全科医疗咨询前自行完成自动签到筛查时,检查抑郁症筛查呈阳性的患者数量。

设计

描述性横断面研究。

地点

英国西米德兰兹郡的10家全科诊所。招募工作于2023年3月开始,2023年6月结束。

参与者

所有18岁及以上的患者,在为期3周的招募期间,被邀请参与任何预先预约的全科医疗自动签到筛查。

主要和次要结局指标

使用Whooley病例发现研究问题筛查出抑郁症呈阳性的患者数量是主要结局指标。次要结局指标包括:完成筛查反应中的人口统计学和(全科医疗水平的)贫困差异。

结果

73.5%(n = 3666)自行完成自动签到筛查的患者参与了初级保健中抑郁症病例发现(CAIRO)研究,(61.1%(n = 2239)为女性,平均年龄55.0岁(18 - 96岁,标准差 = 18.5))。28.3%(n = 1039)的参与者对两个Whooley研究问题中的至少一个给出了阳性反应(女性为31.2%,男性为23.8%)。女性、年龄在35岁至49岁之间的人以及来自贫困程度更高诊所的人获得的阳性反应明显更多。

结论

超过四分之一的CAIRO参与者对两个Whooley问题中的至少一个给出了阳性反应,这表明在所研究的人群中可能存在未满足的需求。后续研究可以调查在签到时给出的反应在随后的咨询中是否被提出并得到解决。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769b/12182143/fc8ad73ab806/bmjopen-15-6-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769b/12182143/fc8ad73ab806/bmjopen-15-6-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769b/12182143/fc8ad73ab806/bmjopen-15-6-g001.jpg

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Distinguishing emotional distress from mental disorder in primary care: a qualitative exploration of the Four-Dimensional Symptom Questionnaire.
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Temporal patterns in the recorded annual incidence of common mental disorders over two decades in the United Kingdom: a primary care cohort study.二十年来英国常见精神障碍记录发病率的时间模式:一项初级保健队列研究。
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