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Solving the enigma of burst suppression: when a seizure model is mistaken for burst suppression. Comment on Br J Anaesth 2025; 134: 900-2.解开爆发抑制之谜：当癫痫发作模型被误认为是爆发抑制时。对《英国麻醉学杂志》2025年；134: 900 - 2的评论
Br J Anaesth. 2025 Jun 18. doi: 10.1016/j.bja.2025.06.001.
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本文引用的文献

1
Solving the enigma of burst suppression.破解爆发抑制之谜。
Br J Anaesth. 2025 Apr;134(4):900-902. doi: 10.1016/j.bja.2024.12.013. Epub 2025 Feb 21.
2
Synchronicity of pyramidal neurones in the neocortex dominates isoflurane-induced burst suppression in mice.新皮层中锥体神经元的同步性主导了异氟烷诱导的小鼠爆发性抑制。
Br J Anaesth. 2025 Apr;134(4):1122-1133. doi: 10.1016/j.bja.2024.10.052. Epub 2025 Jan 30.
3
Parvalbumin Interneuron Dysfunction in Neurological Disorders: Focus on Epilepsy and Alzheimer's Disease.神经紊乱疾病中的颗粒蛋白前体细胞衍生蛋白（Parvalbumin）中间神经元功能障碍：聚焦于癫痫和阿尔茨海默病。
Int J Mol Sci. 2024 May 19;25(10):5549. doi: 10.3390/ijms25105549.
4
Parvalbumin Role in Epilepsy and Psychiatric Comorbidities: From Mechanism to Intervention.小清蛋白在癫痫和精神疾病共病中的作用：从机制到干预
Front Integr Neurosci. 2022 Feb 17;16:765324. doi: 10.3389/fnint.2022.765324. eCollection 2022.
5
American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2021 Version.美国临床神经生理学会标准化重症监护脑电图术语：2021版
J Clin Neurophysiol. 2021 Jan 1;38(1):1-29. doi: 10.1097/WNP.0000000000000806.
6
The impact of silencing feed-forward parvalbumin-expressing inhibitory interneurons in the cortico-thalamocortical network on seizure generation and behaviour.沉默皮质-丘脑-皮质网络中表达前馈型 parvalbumin 的抑制性中间神经元对癫痫发作和行为的影响。
Neurobiol Dis. 2019 Dec;132:104610. doi: 10.1016/j.nbd.2019.104610. Epub 2019 Sep 5.
7
Pharmacokinetic and pharmacodynamic actions of clozapine-N-oxide, clozapine, and compound 21 in DREADD-based chemogenetics in mice.氯氮平-N-氧化物、氯氮平和化合物 21 在基于 DREADD 的化学遗传学中的药代动力学和药效学作用在小鼠体内的研究。
Sci Rep. 2019 Mar 14;9(1):4522. doi: 10.1038/s41598-019-41088-2.
8
Selective Silencing of Hippocampal Parvalbumin Interneurons Induces Development of Recurrent Spontaneous Limbic Seizures in Mice.海马小白蛋白中间神经元的选择性沉默诱导小鼠复发性自发性边缘性癫痫发作的发生。
J Neurosci. 2017 Aug 23;37(34):8166-8179. doi: 10.1523/JNEUROSCI.3456-16.2017. Epub 2017 Jul 21.
9
Enhanced Burst-Suppression and Disruption of Local Field Potential Synchrony in a Mouse Model of Focal Cortical Dysplasia Exhibiting Spike-Wave Seizures.在表现出棘波-慢波癫痫发作的局灶性皮质发育异常小鼠模型中增强的爆发抑制和局部场电位同步性破坏
Front Neural Circuits. 2016 Nov 10;10:93. doi: 10.3389/fncir.2016.00093. eCollection 2016.
10
General anesthesia, sleep, and coma.全身麻醉、睡眠与昏迷。
N Engl J Med. 2010 Dec 30;363(27):2638-50. doi: 10.1056/NEJMra0808281.

Solving the enigma of burst suppression: when a seizure model is mistaken for burst suppression. Comment on Br J Anaesth 2025; 134: 900-2.

作者信息

Aksenov Daniil P, Doubovikov Evan D

机构信息

Department of Anesthesiology, Endeavor Health, Evanston, IL, USA; Department of Radiology, Endeavor Health, Evanston, IL, USA; University of Chicago, Pritzker School of Medicine, Chicago, IL, USA; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.

Department of Radiology, Endeavor Health, Evanston, IL, USA.

出版信息

Br J Anaesth. 2025 Jun 18. doi: 10.1016/j.bja.2025.06.001.

DOI:10.1016/j.bja.2025.06.001
PMID:40537323
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12309673/
Abstract
摘要