Soldati Giulia, Turrina Stefania, Ausania Francesco
Department of Diagnostics and Public Health, Section of Forensic Medicine, University of Verona, Verona, Italy.
Int J Legal Med. 2025 Jun 20. doi: 10.1007/s00414-025-03539-6.
The Investigator Argus Y-28 QS Kit is a 27-locus, six-dye multiplex, which includes six rapidly mutating Short Tandem Repeats (RM Y-STRs).
A new text file containing the optimized panel and bin sets for GeneMapper ID-X Software v1.6 has been prepared. In addition, an internal validation study was conducted on the Investigator Argus Y-28 QS kit using the SeqStudio™ Genetic Analyzer for HID.
The full results of that study are presented here, including data on precision, sensitivity, reproducibility, stutter determination, and reduction volume analysis. A concordance study and three case reports are documented. Finally, the kit was successfully used to conduct a proficiency test.
The obtained findings achieved a satisfactory performance of the Investigator Argus Y-28 QS Kit on the SeqStudio™ Genetic Analyzer for HID.
Investigator Argus Y-28 QS试剂盒是一种包含27个基因座、六种染料的多重检测试剂盒，其中包括六个快速突变的短串联重复序列（RM Y-STRs）。
已准备了一个新的文本文件，其中包含针对GeneMapper ID-X Software v1.6的优化面板和分型组。此外，使用SeqStudio™遗传分析仪对Investigator Argus Y-28 QS试剂盒进行了内部验证研究，用于人类身份识别。
在此展示该研究的完整结果，包括精密度、灵敏度、重现性、拖尾判定和减少体积分析的数据。记录了一致性研究和三个案例报告。最后，该试剂盒成功用于进行能力验证测试。
所获得的结果表明Investigator Argus Y-28 QS试剂盒在SeqStudio™遗传分析仪上用于人类身份识别时具有令人满意的性能。
