Pittman D M, Smith L E
Dis Colon Rectum. 1985 Nov;28(11):836-43. doi: 10.1007/BF02555488.
A series of 126 colostomy closures was analyzed to evaluate factors contributing to morbidity. There were no deaths, but there was a 33 percent complication rate. Patients with penetrating abdominal trauma and foreign-body rectal perforations had fewer serious complications following colostomy closures than patients with diverticulitis or cancer. No significant difference was found in the anastomotic leak rate, length of surgery or length of hospitalization in patients with sutured or stapled anastomoses. Most patients in this series had end colostomies that required limited resection and anastomoses. Complication rates were comparable with previous series, which consisted predominantly of loop colostomy closures. The incidence of surgical complications was not related to the time interval between colostomy formation and closure. Timing of closure, however, significantly influenced the complication rate in two specific patient groups: patients with intraperitoneal colon perforation at the initial procedure when closure was performed within four weeks, and patients with surgical complications at the time of colostomy creation if they underwent closure within eight weeks. Early closures in patients still recovering from colostomy complications were associated with the highest incidence of anastomotic leak. Wound infections at stoma sites were decreased by leaving the skin open. The average hospitalization was 11.1 days for patients without complications, 15.5 days for those with wound infection, 18.5 days for patients with ileus, and 20.4 days for patients with anastomotic leaks. This study illustrates that the optimal time for colostomy closure must be determined on an individual basis. The morbidity can be minimized by delaying closure in specific groups of patients for one to two months. Delaying closure for an arbitrary time interval in all patients, however, is not warranted.
对126例结肠造口关闭术进行了分析,以评估导致发病的因素。无死亡病例,但并发症发生率为33%。与憩室炎或癌症患者相比,穿透性腹部创伤和直肠异物穿孔患者在结肠造口关闭术后严重并发症较少。缝合或吻合器吻合的患者在吻合口漏发生率、手术时间或住院时间方面未发现显著差异。本系列中的大多数患者行末端结肠造口术,需要有限的切除和吻合。并发症发生率与之前主要为袢式结肠造口关闭术的系列研究相当。手术并发症的发生率与结肠造口形成与关闭之间的时间间隔无关。然而,关闭时机对两个特定患者群体的并发症发生率有显著影响:初次手术时腹腔内结肠穿孔且在四周内进行关闭的患者,以及结肠造口时出现手术并发症且在八周内进行关闭的患者。仍在从结肠造口并发症中恢复的患者早期关闭与吻合口漏的最高发生率相关。开放皮肤可减少造口部位的伤口感染。无并发症患者的平均住院时间为11.1天,伤口感染患者为15.5天,肠梗阻患者为18.5天,吻合口漏患者为20.4天。本研究表明,结肠造口关闭的最佳时间必须根据个体情况确定。通过将特定患者群体的关闭时间延迟一到两个月,可将发病率降至最低。然而,在所有患者中任意延迟关闭时间是没有必要的。