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袢式结肠造口术和端式结肠造口术关闭术后的发病率和死亡率

Rates of morbidity and mortality after closure of loop and end colostomy.

作者信息

Mileski W J, Rege R V, Joehl R J, Nahrwold D L

机构信息

Department of Surgery, Northwestern University Medical School, Chicago, Illinois.

出版信息

Surg Gynecol Obstet. 1990 Jul;171(1):17-21.

PMID:2360144
Abstract

The purported ease and safety of closure of loop colostomy are cited as reasons for avoiding end colostomy, with or without resection. However, data comparing the complications of loop colostomy closure and end colostomy takedown and anastomosis are sparse. We analyzed data from 93 consecutive colostomy closures, of which 62 were loop and 31 were end colostomies. The two groups were comparable with respect to age, the underlying disease and risk factors, such as coronary artery disease, diabetes, hypertension, steroid dependence, hypoalbuminemia and smoking. Closure of end colostomies took longer and was associated with more loss of blood than closure of loop colostomies. However, the mortality rates for closure of loop (4.8 per cent) and end (3.2 per cent) colostomies were not significantly different. The complication rates were identical (16 per cent). Although none of the other risk factors were associated with increased rates of mortality or morbidity, the detrimental effects of steroid dependence and preoperative hypoalbuminemia were striking. All four of the deaths and 60 per cent of the complications occurred in patients with steroid dependence or hypoalbuminemia, or both. The rates of wound infection after primary or secondary closure of the stoma site were not significantly different. We concluded that loop colostomy closure is not associated with fewer complications than closure of end colostomy, even though the latter takes longer and is more difficult. Hypoalbuminemic and steroid-dependent patients should undergo colostomy closure with caution, if at all. Primary closure of the stomal site is safe and reduces the length of hospital stay.

摘要

回肠袢式造口关闭术据称操作简便且安全,这被视为避免行端式结肠造口术(无论是否同时行切除术)的理由。然而,关于比较回肠袢式造口关闭术与端式结肠造口还纳术及吻合术并发症的数据却很稀少。我们分析了连续93例结肠造口关闭术的数据,其中62例为回肠袢式造口关闭术,31例为端式结肠造口关闭术。两组在年龄、基础疾病以及冠状动脉疾病、糖尿病、高血压、类固醇依赖、低蛋白血症和吸烟等危险因素方面具有可比性。端式结肠造口关闭术所需时间更长,且与术中失血量更多相关。然而,回肠袢式造口关闭术(4.8%)和端式结肠造口关闭术(3.2%)的死亡率并无显著差异。并发症发生率相同(16%)。虽然其他危险因素均未与死亡率或发病率的增加相关,但类固醇依赖和术前低蛋白血症的有害影响却很显著。所有4例死亡病例以及60%的并发症均发生在类固醇依赖或低蛋白血症患者或两者兼具的患者中。造口部位一期或二期关闭后的伤口感染率并无显著差异。我们得出结论,回肠袢式造口关闭术并不比端式结肠造口关闭术的并发症少,尽管后者所需时间更长且操作更困难。低蛋白血症和类固醇依赖患者如需行结肠造口关闭术应谨慎考虑。造口部位一期关闭是安全的,且可缩短住院时间。

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