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肠造口还纳术后的伤口感染:一期缝合与皮下连续缝合比较。

Wound infection following stoma takedown: primary skin closure versus subcuticular purse-string suture.

机构信息

Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota, 420 Delaware Street SE, MMC 450, Minneapolis, MN 55455, USA.

出版信息

World J Surg. 2010 Dec;34(12):2877-82. doi: 10.1007/s00268-010-0753-4.

Abstract

BACKGROUND

Stoma closure has been associated with a high rate of surgical site infection (SSI) and the ideal stoma-site skin closure technique is still debated. The aim of this study was to compare the rate of SSI following primary skin closure (PC) versus a skin-approximating, subcuticular purse-string closure (APS).

METHODS

All consecutive patients undergoing stoma closure between 2002 and 2007 by two surgeons at a single tertiary-care institution were retrospectively assessed. Patients who had a new stoma created at the same site or those without wound closure were excluded. The end point was SSI, determined according to current CDC guidelines, at the stoma closure site and/or the midline laparotomy incision.

RESULTS

There were 61 patients in the PC group (surgeon A: 58 of 61) and 17 in the APS group (surgeon B: 16 of 17). The two groups were similar in baseline and intraoperative characteristics, except that patients in the PC group were more often diagnosed with benign disease (p = 0.0156) and more often had a stapled anastomosis (p = 0.002). The overall SSI rate was 14 of 78 (18%). All SSIs occurred in the PC group (14 of 61 vs. 0 of 17, p = 0.03).

CONCLUSIONS

Our study suggests that a skin-approximating closure with a subcuticular purse-string of the stoma site leads to less SSI than a primary closure. Randomized studies are needed to confirm our findings and assess additional end points such as healing time, cost, and patient satisfaction.

摘要

背景

造口关闭后与高的手术部位感染(SSI)发生率相关,理想的造口部位皮肤关闭技术仍存在争议。本研究旨在比较一期皮肤关闭(PC)与皮内近似荷包缝合关闭(APS)后的 SSI 发生率。

方法

回顾性评估了 2002 年至 2007 年间,由两位外科医生在一家单一的三级保健机构连续进行的所有造口关闭患者。排除在同一部位创建新造口或未行伤口闭合的患者。终点是根据当前 CDC 指南确定的造口关闭部位和/或中线剖腹切口处的 SSI。

结果

PC 组有 61 例患者(外科医生 A:61 例中的 58 例),APS 组有 17 例患者(外科医生 B:17 例中的 16 例)。两组在基线和术中特征方面相似,除了 PC 组患者更常被诊断为良性疾病(p=0.0156)和更常行吻合钉吻合(p=0.002)外。总的 SSI 发生率为 78 例中的 14 例(14/78)。所有 SSI 均发生在 PC 组(61 例中的 14 例 vs. 17 例中的 0 例,p=0.03)。

结论

我们的研究表明,与一期闭合相比,皮内近似荷包缝合关闭造口部位可减少 SSI。需要进行随机研究以证实我们的发现,并评估其他终点,如愈合时间、成本和患者满意度。

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