Tandon Devansh, Azzopardi Matthew, Fenn Dominic, Parmar Mira, Jain Saurabh
University College London Medical School London UK.
Department of Ophthalmology Royal Free NHS Foundation Trust London UK.
Pediatr Investig. 2025 Feb 14;9(2):167-171. doi: 10.1002/ped4.12470. eCollection 2025 Jun.
Horner syndrome (HS) is a rare neurological disorder arising from disruption of the oculosympathetic pathway. Pediatric HS is uncommon and may be congenital, but underlying sinister causes need to be excluded.
An 18-week-old boy presented with right peri-orbital swelling, initially thought to be pre-septal cellulitis. Further ophthalmic review revealed a right-sided HS. Imaging identified a probable cervical neuroblastoma, leading to an urgent referral to oncology.
Early recognition of pediatric HS is crucial as it may signal underlying malignancies like neuroblastoma. Atypical presentations with sequential or intermittent symptoms make diagnosis challenging. Comprehensive imaging and multidisciplinary care ensure timely diagnosis and management.
霍纳综合征(HS)是一种罕见的神经系统疾病,由眼交感神经通路中断引起。小儿霍纳综合征并不常见,可能是先天性的,但需要排除潜在的严重病因。
一名18周大的男孩出现右眼眶周肿胀,最初被认为是眶隔前蜂窝织炎。进一步的眼科检查发现右侧霍纳综合征。影像学检查发现可能是颈部神经母细胞瘤,遂紧急转诊至肿瘤科。
早期识别小儿霍纳综合征至关重要,因为它可能预示着潜在的恶性肿瘤,如神经母细胞瘤。具有相继或间歇性症状的非典型表现使诊断具有挑战性。全面的影像学检查和多学科护理可确保及时诊断和治疗。