Madsen P M, Braendstrup O
Dis Colon Rectum. 1985 Sep;28(9):676-7. doi: 10.1007/BF02553451.
The differentiation of 39 diagnostic biopsies, as determined by histologic grading, and that of the corresponding 39 rectal carcinomas were compared. About 60 percent of grade I tumors were diagnosed by grade I biopsies, while about 90 percent of grade II and only about 40 percent of grade III tumors were diagnosed by grade II and grade III biopsies, respectively. The results indicate caution when biopsy grading is used as a guidance to therapy, especially of poorly differentiated tumors.
通过组织学分级确定的39份诊断性活检样本的分化情况,与相应的39例直肠癌的分化情况进行了比较。约60%的I级肿瘤通过I级活检被诊断出来,而约90%的II级肿瘤和仅约40%的III级肿瘤分别通过II级和III级活检被诊断出来。结果表明,当活检分级用作治疗指导时应谨慎,尤其是对于低分化肿瘤。