Greenbaum J, Cockcroft D, Hargreave F E, Dolovich J
J Allergy Clin Immunol. 1977 Jun;59(6):437-9. doi: 10.1016/0091-6749(77)90006-9.
Sodium cromoglycate (SCG), in a 4% solution instilled into each eye 4 times daily, was compared with placebo in a double-blind, noncrossover trial in 30 matched patients with troublesome ragweed pollen-induced conjunctivitis. In the SCG group, eye symptom scores were significantly less (p = 0.05), and all patients judged that their symptoms were improved over the previous year (p less than 0.05). Less antihistamine was used by the SCG group but the difference was not significant. It was concluded that SCG was effective in the treatment of ragweed-induced seasonal allergic conjunctivitis.
在一项双盲、非交叉试验中,将30例匹配的豚草花粉诱发的难治性结膜炎患者分为两组,一组每日4次向每只眼睛滴入4%的色甘酸钠溶液,另一组使用安慰剂。色甘酸钠组的眼部症状评分显著更低(p = 0.05),所有患者均判断其症状较前一年有所改善(p < 0.05)。色甘酸钠组使用的抗组胺药较少,但差异不显著。得出的结论是,色甘酸钠对治疗豚草诱发的季节性过敏性结膜炎有效。