Wang Zhuoran, Li Haiting, Du Xiaoping, Wang Qiong, Zhang Yating, Wang Huifang
Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Department of First Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, China.
Ann Clin Transl Neurol. 2025 Aug;12(8):1717-1722. doi: 10.1002/acn3.70110. Epub 2025 Jun 21.
Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias. We present a case of paroxysmal kinesigenic dyskinesias secondary to human herpesvirus 6A encephalitis for the first time, and review the literature on paroxysmal dyskinesias secondary to central nervous system infection. This case highlights the importance of differentiating primary from secondary paroxysmal dyskinesias. Early anti-infection and immunotherapy may be the key to treating this type of disease.
发作性运动障碍包括一系列以间歇性不自主运动为特征的病症,其中发作性运动诱发性运动障碍是最常见的表型。中枢神经系统感染是发作性运动障碍的罕见病因。我们首次报告了一例继发于人类疱疹病毒6A型脑炎的发作性运动诱发性运动障碍病例,并回顾了中枢神经系统感染继发发作性运动障碍的相关文献。该病例凸显了区分原发性和继发性发作性运动障碍的重要性。早期抗感染和免疫治疗可能是治疗这类疾病的关键。