Handzel Daniel M, Abdallah Chiraz Ben, Ladewig Markus S, Sekundo Walter
Philipps-University Marburg, Campus Fulda, Fulda, Germany.
Augenzentrum Osthessen, Standort Augenaerzte im Altstadt-Carree, Dalbergstr. 22, 36037, Fulda, Germany.
Graefes Arch Clin Exp Ophthalmol. 2025 Jun 21. doi: 10.1007/s00417-025-06867-w.
To study the properties of different ophthalmic viscosurgical devices (OVD) in respect of their ability to create and maintain high intraocular pressure (IOP) during the creation of a continuous curvilinear capsulorhexis (CCC).
In this randomized interventional study IOP was measured using rebound tonometry with sterilized probes immediately before the beginning of the CCC and immediately afterwards during cataract surgery. The study included 177 eyes in four groups using two different OVD - hyaluronic acid (HA) and a combination of HA and hydroxy propylmethylcellulosis (HPMC) according to the soft shell-technique (SST) - and two different instruments, Utrata forceps (UF) and 26 g cystotome (RN).
The drop in intraocular pressure (IOP) during capsulorhexis was measured at 57.0 ± 12.2 mmHg in eyes treated with HA (90) and 63.1 ± 13.4 mmHg in eyes treated with SS (87). The difference in IOP reduction between HA and SS did not reach statistical significance (p = 0.060).
The use of different OVD did not result in a significant difference in IOP drop. As the soft shell-technique has shown superiority in respect of endothelial protection, these results should encourage cataract surgeon to resort to the soft shell-technique more often if not use it as a standard technique.
研究不同眼科粘弹剂(OVD)在连续环形撕囊(CCC)过程中产生并维持高眼压(IOP)的能力。
在这项随机干预研究中,在白内障手术开始前及CCC操作刚结束后,立即使用消毒探头通过回弹眼压计测量眼压。该研究纳入了四组共177只眼,使用两种不同的OVD——透明质酸(HA)以及根据软壳技术(SST)使用的HA与羟丙基甲基纤维素(HPMC)的组合——以及两种不同器械,Utrata镊(UF)和26G截囊针(RN)。
使用HA治疗的90只眼中,撕囊过程中的眼压下降值为57.0±12.2 mmHg,使用软壳技术(SS)治疗的87只眼中,眼压下降值为63.1±13.4 mmHg。HA与SS之间眼压降低的差异未达到统计学意义(p = 0.060)。
使用不同的OVD在眼压下降方面未产生显著差异。由于软壳技术在保护内皮方面已显示出优势,这些结果应鼓励白内障手术医生如果不将其作为标准技术,也应更频繁地采用软壳技术。