Iwasa Yuhei, Iwata Keisuke, Tezuka Ryuichi, Iwashita Takuji, Uemura Shinya, Iwata Shota, Ohashi Yosuke, Murayama Yuki, Shimizu Masahito
Department of Gastroenterology, Gifu Municipal Hospital, 7-1 Kashimacho, Gifu, 500-8513, Japan.
Department of Gastroenterology, Gifu University Graduate School of Medicine, Gifu, Japan.
Clin J Gastroenterol. 2025 Jun 22. doi: 10.1007/s12328-025-02168-1.
We describe three cases in which plasmapheresis was effective for persistent obstructive jaundice, even after biliary drainage. All three cases involved resectable or borderline resectable malignant tumors that caused obstructive jaundice. Jaundice is refractory to biliary drainage and medication and results in prolonged hyperbilirubinemia. Plasmapheresis led to improvements in all cases. Plasmapheresis may be a treatment option for persistent obstructive jaundice resistant to standard therapies.
我们描述了三例即使在进行胆管引流后血浆置换仍对持续性梗阻性黄疸有效的病例。所有三例均涉及导致梗阻性黄疸的可切除或临界可切除恶性肿瘤。黄疸对胆管引流和药物治疗均无效，导致长时间的高胆红素血症。血浆置换在所有病例中均带来了改善。对于对标准治疗有抵抗的持续性梗阻性黄疸，血浆置换可能是一种治疗选择。
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