Zhang Min, Zhang Jingjing, Zhao Kelei, Yuan Xiaohan, Zhang Jinghang, Liu Yanting, Lu Ping
Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Department of Pathology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Clin Respir J. 2025 Jun;19(6):e70081. doi: 10.1111/crj.70081.
This case report features a patient with an invasive thymoma. The patient presented with an anterior mediastinal mass that invaded the left brachiocephalic trunk vein, resulting in the formation of a carcinoma thrombus in the right atrium, superior vena cava, left brachiocephalic trunk vein, and left internal jugular vein (Masaoka stage IV). No indication for surgery was assessed by surgical consultation. After six cycles of chemotherapy and chest radiotherapy, the tumor size decreased from 72.43 to 24 mm, showing a significant improvement in patient efficacy. After a follow-up of 50 months, the patient remained well, without local recurrence or distal metastasis, and maintained a partial response (PR).
本病例报告介绍了一名侵袭性胸腺瘤患者。该患者表现为前纵隔肿块，侵犯了左头臂干静脉，导致右心房、上腔静脉、左头臂干静脉和左颈内静脉形成癌栓（Masaoka 分期 IV 期）。经外科会诊评估，无手术指征。经过六个周期的化疗和胸部放疗后，肿瘤大小从 72.43 毫米缩小至 24 毫米，患者疗效显著改善。经过 50 个月的随访，患者情况良好，无局部复发或远处转移，维持部分缓解（PR）。
