Uzbak Sajedeh, Walsh Leah, Smith David, Wan Michael J
Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Department of Clinical Vision Science, Dalhousie University, Halifax, Nova Scotia, Canada; Department of Ophthalmology, The IWK Health Centre, Halifax, Nova Scotia, Canada.
Department of Clinical Vision Science, Dalhousie University, Halifax, Nova Scotia, Canada; Department of Ophthalmology, The IWK Health Centre, Halifax, Nova Scotia, Canada.
J AAPOS. 2025 Aug;29(4):104252. doi: 10.1016/j.jaapos.2025.104252. Epub 2025 Jun 20.
The prolonged monocular occlusion (PMO) test is used to eliminate tenacious proximal fusion in patients with divergence excess intermittent exotropia. The minimum necessary duration of PMO is unknown. This study was designed to determine whether 15 minutes of PMO test is comparable to 45 minutes of PMO.
This prospective, randomized, observational study included 22 patients (5-14 years of age) diagnosed with divergence excess intermittent exotropia. The main outcome measure was the subclassification of divergence excess intermittent exotropia. The secondary outcomes were the effect of 15 minutes and 45 minutes of PMO on the size of the deviation, the near-distance disparity, and the accommodative convergence-accommodation (AC/A) ratio estimates.
The number of patients classified as simulated, high AC/A ratio, and true divergence excess intermittent exotropia were identical following 15 minutes and 45 minutes of PMO. There were no statistically or clinically significant differences in the size of the near and distance deviations, the near-distance disparity, or the AC/A ratio following 15 and 45 minutes of PMO.
In our patient cohort, a period of 15 minutes of PMO was sufficient to unmask the true underlying deviation at near and properly subclassify divergence excess intermittent exotropia patients.
长时间单眼遮盖(PMO)试验用于消除散开过强型间歇性外斜视患者顽固的近距离融合。PMO的最短必要时长尚不清楚。本研究旨在确定15分钟的PMO试验是否与45分钟的PMO试验效果相当。
这项前瞻性、随机、观察性研究纳入了22例诊断为散开过强型间歇性外斜视的患者(年龄5 - 14岁)。主要结局指标是散开过强型间歇性外斜视的亚分类。次要结局是15分钟和45分钟的PMO对斜视度大小、近距离视差以及调节性集合-调节(AC/A)比值估计的影响。
在15分钟和45分钟的PMO试验后,被分类为模拟型、高AC/A比值型和真正的散开过强型间歇性外斜视的患者数量相同。在15分钟和45分钟的PMO试验后,近距和远距离斜视度大小、近距离视差或AC/A比值在统计学或临床上均无显著差异。
在我们的患者队列中,15分钟的PMO时长足以揭示近距离真正的潜在斜视度,并对散开过强型间歇性外斜视患者进行正确的亚分类。