Srivastava Prakhar, Singh Vishvender, Srivastava Prachi, Misri Rachita, Khunger Niti
Department of Dermatology and STD, Pandit Madan Mohan Malviya Hospital, New Delhi, India.
Department of Dermatology and STD, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Indian J Sex Transm Dis AIDS. 2025 Jan-Jun;46(1):64-66. doi: 10.4103/ijstd.ijstd_19_24. Epub 2025 Jun 9.
Kissing nevi are rare congenital melanocytic nevi (CMN) that develop on adjacent skin areas separated during embryogenesis. We report a 25-year-old uncircumcised man with two asymptomatic brownish-black macules on the dorsolateral glans penis and inner foreskin, aligning as "kissing" lesions. Dermoscopy showed a structureless brown center with peripheral pigment globules. Their embryological origin involves melanoblast migration before or during preputial placode separation. While typically benign, rare cases of malignant transformation necessitate regular monitoring. Treatment options, including surgery and laser therapy, should balance functional and aesthetic considerations. This case highlights the clinical significance of this unique entity.
接吻痣是罕见的先天性黑素细胞痣(CMN),发生于胚胎发育过程中分离的相邻皮肤区域。我们报告一名25岁未行包皮环切术的男性,其阴茎背外侧龟头和包皮内板有两个无症状的棕黑色斑,呈“接吻”样病变排列。皮肤镜检查显示中央为无结构的褐色,周边有色素球。其胚胎学起源涉及包皮原基分离之前或期间黑素母细胞的迁移。虽然通常为良性,但罕见的恶变病例需要定期监测。治疗选择包括手术和激光治疗,应在功能和美观方面进行权衡。本病例突出了这一独特实体的临床意义。