Al Ayoubi Mohamad, Abi Dargham Sally H, Hsayan Fatima I, Sadek Maroun H, Abi Abboud Antoine
Gastroenterology, Lebanese University Faculty of Medicine, Beirut, LBN.
Internal Medicine, Lebanese University Faculty of Medicine, Beirut, LBN.
Cureus. 2025 May 22;17(5):e84620. doi: 10.7759/cureus.84620. eCollection 2025 May.
Upper gastrointestinal bleed is a frequent medical emergency, which may arise from multiple pathologies. Metastatic lesions to the stomach and duodenum, although rare, may be an underlying cause. Specifically, metastasis from a primary cervical malignancy is extremely infrequent, with only a few cases reported in the literature. In addition, concomitant metastatic lesions in the stomach and duodenum from cervical cancer have not been reported yet. We present the case of a 46-year-old female patient known to have cervical squamous cell carcinoma, metastatic to the lungs, bone, and liver, presenting for melena and hematemesis. Endoscopy revealed ulcerating mass lesions in the stomach and duodenum, confirmed as metastatic epidermoid carcinoma on pathology. Hence, metastasis to the stomach and the duodenum should be kept in mind in a patient with cervical cancer presenting with upper gastrointestinal symptoms.
上消化道出血是一种常见的医疗急症，可能由多种病理状况引起。胃和十二指肠的转移性病变虽然罕见，但可能是潜在病因。具体而言，原发性宫颈恶性肿瘤的转移极为罕见，文献中仅报道过少数病例。此外，尚未有宫颈癌同时在胃和十二指肠发生转移性病变的报道。我们报告一例46岁女性患者，已知患有宫颈鳞状细胞癌，已转移至肺、骨和肝，现因黑便和呕血前来就诊。内镜检查发现胃和十二指肠有溃疡性肿块病变，病理检查确诊为转移性表皮样癌。因此，对于出现上消化道症状的宫颈癌患者，应考虑胃和十二指肠转移的可能性。
