Breast reconstruction surgery is an important part of breast cancer treatment. However, implant-based breast reconstruction is associated with a number of complications, such as infection, seroma, prosthesis exposure, and skin erythema. In this study, we propose a novel surgical technique for implant-based breast reconstruction-the triple-plane technique. This technique positions the prosthesis in a complete submuscular plane. Medially, it is subpectoral, and inferolaterally it is covered by a flap of serratus anterior and latissimus dorsi fascia. As such, the prosthesis is not in contact with the skin, thereby reducing postoperative complications. This article reports on the breast reconstruction results of 96 breast cancer patients who underwent unilateral breast reconstruction surgery using the triple-plane technique at Hunan Cancer Hospital. The results show that breast appearance after surgery was rated as excellent by 92 (95.83%) patients, and good by 4 (4.17%) patients. The average operation time, surgical incision, intraoperative blood loss, and hospitalization time of patients were 88.40±12.13 minutes, 12.24±4.01 cm, 46.40±10.73 mL, and 7.23±1.00 days, respectively. Skin necrosis at the edge of the incision was observed in 1 (1.04%) patient, which healed normally after debridement and closure. The scores of BREAST-Q patient-reported outcome measure ranged from 80 to 100 points for all of the patients. These results demonstrate that the triple-plane technique offers a novel and safe technique for breast reconstruction surgery.