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由……引起的耐药皮肤癣菌病的出现:泰国的首个病例系列

Emergence of resistant dermatophytosis caused by : First case series in Thailand.

作者信息

Prunglumpoo Sutsarun, Krongboon Kunyanut, Intarachaieua Klaichan, Kazushi Anzawa, Bunnag Thareena, Paunrat Wattamon, Komkhong Wanchanida

机构信息

Institute of Dermatology, Bangkok, Thailand.

Kanazawa Medical University Hospital, Japan.

出版信息

Med Mycol Case Rep. 2025 Jun 7;48:100713. doi: 10.1016/j.mmcr.2025.100713. eCollection 2025 Jun.

Abstract

We identified 5 Thai patients diagnosed with infection after screening of patients with culture results consistent with complex who had negative urease test and confirmed by molecular analysis in DNA sequencing at the internal transcribed spacer region, including abnormalities in the Squalene epoxidase gene in 2 patients, which confirmed the spread of terbinafine resistant dermatophytosis in Thailand.

摘要

我们在对培养结果与复杂性感染相符、尿素酶试验呈阴性且经内转录间隔区DNA测序分子分析确认的患者进行筛查后,确定了5名泰国患者感染了该病,其中2名患者的角鲨烯环氧酶基因存在异常,这证实了特比萘芬耐药皮肤癣菌病在泰国的传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f803/12179712/1598ac947cbb/ga1.jpg

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