接受胸部男性化手术患者的偶然非典型性：一项观察性系列研究
Incidental Atypia in Patients Undergoing Chest Masculinization Surgery: An Observational Series.
作者信息
Kolbow Madison, Cohen Jade, Prathibha Saranya, Marmor Schelomo, Buckley Marie-Claire, Hui Jane Yuet Ching
机构信息
University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Chicago, Chicago, Illinois, USA.
出版信息
Transgend Health. 2025 Jun 5;10(3):297-301. doi: 10.1089/trgh.2023.0011. eCollection 2025 Jun.
This retrospective study investigated the incidence of breast atypia and breast cancer (BC) in patients undergoing chest masculinization surgery. Of the 880 patients included, 7 (0.8%) were diagnosed with atypia and none with BC. The median age at surgery for patients without and with atypia was 25.0 and 36.0 years, respectively. Preoperative testosterone therapy utilization was similar among patients with atypia (71%) and patients without (79%). No patients with atypia were diagnosed with subsequent BC during a median follow-up of 37 months. Appropriate BC screening and risk management for patients undergoing chest masculinization surgery should be further elucidated.
这项回顾性研究调查了接受胸部男性化手术患者的乳腺异型增生和乳腺癌（BC）发病率。在纳入的880例患者中，7例（0.8%）被诊断为异型增生，无患者被诊断为乳腺癌。无异型增生和有异型增生患者的手术中位年龄分别为25.0岁和36.0岁。异型增生患者（71%）和无异型增生患者（79%）术前睾酮治疗的使用率相似。在中位随访37个月期间，没有异型增生患者被诊断为后续乳腺癌。对于接受胸部男性化手术的患者，应进一步阐明适当的乳腺癌筛查和风险管理。
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