Ponmattam Jamie, Machado Marcia M T, Scott Valerie, Claro Rafael, Castro Marcia C
Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, USA.
Department of Public Health, University Federal of Ceara, Fortaleza, Brazil.
IJID Reg. 2025 May 14;15:100660. doi: 10.1016/j.ijregi.2025.100660. eCollection 2025 Jun.
This study aimed to examine the attitudes toward dengue vaccine acceptance for adults and children and expected changes in vector control behaviors post-vaccination in three Brazilian cities.
From March to June 2022, a telephone survey asked respondents about their knowledge and attitudes toward vaccination, dengue and vector control, acceptance of a hypothetical dengue vaccine, and anticipated changes in current vector control practices post-vaccination. The risk and protective factors associated with vaccine acceptance and post-vaccination behavior changes were analyzed using rake-weighted logistic regressions.
Most participants were knowledgeable about dengue symptoms (72%), engaged in at least one vector control behavior (92%), and willing to vaccinate themselves and their children (87%). Strong disagreement with the statement that vaccines are effective indicated lower odds of accepting a hypothetical dengue vaccine (odds ratio 0.27, 95% confidence interval: 0.12-0.61), compared with strong agreement. Although most respondents reported that they would not stop or reduce any dengue prevention methods (87-88%), those who trusted in the medical advice of doctors/nurses (odds ratio 2.9, 95% confidence interval: 1.1-7.64) have higher odds of reducing at least one vector control behavior.
Possible changes in vector control behavior after dengue vaccination suggest that routine vector control sensitization and information sharing by medical providers, media communication, and during vaccination campaign events are needed.
本研究旨在调查巴西三个城市的成年人和儿童对登革热疫苗接种的态度，以及接种疫苗后预期的病媒控制行为变化。
2022年3月至6月，通过电话调查询问受访者关于他们对疫苗接种、登革热和病媒控制的知识和态度、对一种假设的登革热疫苗的接受程度，以及接种疫苗后当前病媒控制措施的预期变化。使用加权逻辑回归分析与疫苗接受程度和接种后行为变化相关的风险和保护因素。
大多数参与者了解登革热症状（72%），采取了至少一种病媒控制行为（92%），并且愿意为自己和孩子接种疫苗（87%）。与强烈同意相比，强烈不同意疫苗有效的说法表明接受假设的登革热疫苗的几率较低（优势比0.27，95%置信区间：0.12 - 0.61）。尽管大多数受访者表示他们不会停止或减少任何登革热预防措施（87 - 88%），但那些信任医生/护士医疗建议的人（优势比2.9，95%置信区间：1.1 - 7.64）减少至少一种病媒控制行为的几率更高。
登革热疫苗接种后病媒控制行为可能发生的变化表明，医疗服务提供者、媒体传播以及在疫苗接种活动期间需要进行常规的病媒控制宣传和信息共享。
