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老年患者中大于2厘米肾结石的机器人辅助肾盂切开取石术与微创经皮肾镜取石术手术结果的比较分析:一项为期一年的随访研究

Comparative Analysis of Surgical Outcomes Between Robotic-Assisted Pyelolithotomy and Mini-Percutaneous Nephrolithotomy for Renal Stones Larger Than 2 cm in Older Adults: A One-Year Follow-Up Study.

作者信息

Tu Hong-An, Weng Shu-Chuan, Lin Yu-Hsiang, Chen Chien-Lun, Chen Yu-Ting, Juang Horng-Heng, Hou Chen-Pang

机构信息

Department of Urology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.

Department of Healthcare Management, Yuanpei University of Medical Technology, Hsinchu, Taiwan.

出版信息

Int J Nephrol Renovasc Dis. 2025 Jun 17;18:177-185. doi: 10.2147/IJNRD.S532866. eCollection 2025.

DOI:10.2147/IJNRD.S532866
PMID:40547966
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12182092/
Abstract

PURPOSE

This study aimed to compare the surgical outcomes of robotic-assisted pyelolithotomy (RAPL) and mini-percutaneous nephrolithotomy (mini-PCNL) specifically in older adults with renal stones more than 2cm. We hypothesized that robotic-assisted pyelolithotomy (RAPL) is a safe and effective approach for managing large renal stones (>2 cm) in older adults.

PATIENTS AND METHODS

We retrospectively analyzed 605 patients aged 50-80 years who underwent either RAPL (n=31) or mini-PCNL (n=574) for renal stones >2 cm at Chang Gung Memorial Hospital, Taiwan, between December 2016 and November 2023. Patients were selected based on predefined inclusion and exclusion criteria. Key outcomes measured included stone-free rate, complication rate, hospital stay duration, and re-intervention rates. All patients were followed for at least one year postoperatively.

RESULTS

RAPL patients exhibited a longer total operative time (165.2 vs 127.4 minutes, p = 0.016) but experienced significantly shorter hospital stays (1.8 vs 4.0 days, p < 0.001), lower complication rates (6.5% vs 27.7%, p < 0.05), and higher SFRs (90.3% vs 60.8%, p < 0.001). Blood transfusion, postoperative discomfort, and re-intervention rates were also markedly lower in the RAPL group.

CONCLUSION

For older patients with large renal stones, RAPL is a promising alternative to mini-PCNL, offering better stone clearance, fewer complications, and quicker recovery. Its minimally invasive, tissue-sparing approach benefits those at higher postoperative risk.

摘要

目的

本研究旨在比较机器人辅助肾盂切开取石术(RAPL)和微创经皮肾镜取石术(mini-PCNL)在年龄较大、肾结石直径超过2cm患者中的手术效果。我们假设机器人辅助肾盂切开取石术(RAPL)是治疗老年患者大型肾结石(>2cm)的一种安全有效的方法。

患者与方法

我们回顾性分析了2016年12月至2023年11月期间在台湾长庚纪念医院接受RAPL(n=31)或mini-PCNL(n=574)治疗直径>2cm肾结石的605例年龄在50-80岁的患者。根据预先定义的纳入和排除标准选择患者。测量的主要结局指标包括结石清除率、并发症发生率、住院时间和再次干预率。所有患者术后至少随访一年。

结果

RAPL组患者的总手术时间较长(165.2分钟对127.4分钟,p=0.016),但住院时间明显较短(1.8天对4.0天,p<0.001),并发症发生率较低(6.5%对27.7%,p<0.05),结石清除率较高(90.3%对60.8%,p<0.001)。RAPL组的输血、术后不适和再次干预率也显著较低。

结论

对于患有大型肾结石的老年患者,RAPL是mini-PCNL的一种有前景的替代方法,具有更好的结石清除效果、更少的并发症和更快的恢复。其微创、保留组织的方法对术后风险较高的患者有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef17/12182092/47888d966727/IJNRD-18-177-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef17/12182092/47888d966727/IJNRD-18-177-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef17/12182092/47888d966727/IJNRD-18-177-g0001.jpg

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Percutaneous nephrolithotomy vs. robotic pyelolithotomy for large renal stones: an inverse probability treatment weighting analysis.经皮肾镜取石术与机器人肾盂切开取石术治疗大型肾结石:逆概率加权处理分析
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