Tu Hong-An, Weng Shu-Chuan, Lin Yu-Hsiang, Chen Chien-Lun, Chen Yu-Ting, Juang Horng-Heng, Hou Chen-Pang
Department of Urology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Department of Healthcare Management, Yuanpei University of Medical Technology, Hsinchu, Taiwan.
Int J Nephrol Renovasc Dis. 2025 Jun 17;18:177-185. doi: 10.2147/IJNRD.S532866. eCollection 2025.
This study aimed to compare the surgical outcomes of robotic-assisted pyelolithotomy (RAPL) and mini-percutaneous nephrolithotomy (mini-PCNL) specifically in older adults with renal stones more than 2cm. We hypothesized that robotic-assisted pyelolithotomy (RAPL) is a safe and effective approach for managing large renal stones (>2 cm) in older adults.
We retrospectively analyzed 605 patients aged 50-80 years who underwent either RAPL (n=31) or mini-PCNL (n=574) for renal stones >2 cm at Chang Gung Memorial Hospital, Taiwan, between December 2016 and November 2023. Patients were selected based on predefined inclusion and exclusion criteria. Key outcomes measured included stone-free rate, complication rate, hospital stay duration, and re-intervention rates. All patients were followed for at least one year postoperatively.
RAPL patients exhibited a longer total operative time (165.2 vs 127.4 minutes, p = 0.016) but experienced significantly shorter hospital stays (1.8 vs 4.0 days, p < 0.001), lower complication rates (6.5% vs 27.7%, p < 0.05), and higher SFRs (90.3% vs 60.8%, p < 0.001). Blood transfusion, postoperative discomfort, and re-intervention rates were also markedly lower in the RAPL group.
For older patients with large renal stones, RAPL is a promising alternative to mini-PCNL, offering better stone clearance, fewer complications, and quicker recovery. Its minimally invasive, tissue-sparing approach benefits those at higher postoperative risk.
本研究旨在比较机器人辅助肾盂切开取石术(RAPL)和微创经皮肾镜取石术(mini-PCNL)在年龄较大、肾结石直径超过2cm患者中的手术效果。我们假设机器人辅助肾盂切开取石术(RAPL)是治疗老年患者大型肾结石(>2cm)的一种安全有效的方法。
我们回顾性分析了2016年12月至2023年11月期间在台湾长庚纪念医院接受RAPL(n=31)或mini-PCNL(n=574)治疗直径>2cm肾结石的605例年龄在50-80岁的患者。根据预先定义的纳入和排除标准选择患者。测量的主要结局指标包括结石清除率、并发症发生率、住院时间和再次干预率。所有患者术后至少随访一年。
RAPL组患者的总手术时间较长(165.2分钟对127.4分钟,p=0.016),但住院时间明显较短(1.8天对4.0天,p<0.001),并发症发生率较低(6.5%对27.7%,p<0.05),结石清除率较高(90.3%对60.8%,p<0.001)。RAPL组的输血、术后不适和再次干预率也显著较低。
对于患有大型肾结石的老年患者,RAPL是mini-PCNL的一种有前景的替代方法,具有更好的结石清除效果、更少的并发症和更快的恢复。其微创、保留组织的方法对术后风险较高的患者有益。