Andersson Henrik, Faresjö Tomas, Didriksson Helén, Jonsson Carina, Gagnö Gunilla, Chew Michelle S
Department of Anaesthesia and Intensive Care, Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Department of Health, Medicine and Caring Sciences, General Practice, Linköping University, Linköping, Sweden.
Acta Anaesthesiol Scand. 2025 Jul;69(6):e70081. doi: 10.1111/aas.70081.
To measure chronic, physiological stress using hair cortisol concentrations (HCC) among ICU staff working during the COVID-19 pandemic in Sweden, and to evaluate its relationship with perceived stress (PS), anxiety, and depression, and burnout.
HCC was measured in hair samples of 274 individuals. We tested for differences between females versus males, nurses versus non-nursing, and ordinary versus deployed staff. PS, anxiety, depression, and burnout were measured using validated questionnaires.
Median HCC was 32.6 pg/mg [IQR 21.3-62.3] reflecting physiological stress over 3 months. There were no differences due to sex, profession, and deployment status. Anxiety was detected in 19% and depression in 4% of participants. PS score (23.5 [18.25-29.0]) was higher than previously reported normative data. Burnout was driven by low personal accomplishment. No correlations were found between HCC and PS, anxiety, depression, and burnout.
Chronic, physiological stress measured as HCC was not different due to sex, profession or deployment status. Anxiety and burnout were frequent and depression was reported by a minority. HCC did not correlate with PS, anxiety, depression or burnout.
通过测量瑞典在新冠疫情期间工作的重症监护病房（ICU）工作人员的头发皮质醇浓度（HCC）来评估慢性生理应激，并评估其与感知压力（PS）、焦虑、抑郁和职业倦怠的关系。
对274名个体的头发样本进行HCC测量。我们测试了女性与男性、护士与非护士、普通工作人员与被调配工作人员之间的差异。使用经过验证的问卷测量PS、焦虑、抑郁和职业倦怠。
HCC中位数为32.6 pg/mg[四分位间距21.3 - 62.3]，反映了3个月内的生理应激情况。在性别、职业和调配状态方面没有差异。19%的参与者检测出焦虑，4%的参与者检测出抑郁。PS评分（23.5[18.25 - 29.0]）高于先前报告的标准数据。职业倦怠主要由个人成就感低导致。未发现HCC与PS、焦虑、抑郁和职业倦怠之间存在相关性。
以HCC衡量的慢性生理应激在性别、职业或调配状态方面没有差异。焦虑和职业倦怠较为常见，少数人报告有抑郁症状。HCC与PS、焦虑、抑郁或职业倦怠均无相关性。
