Kose Junko, Davisse-Paturet Camille, Pastorello Anne, Meyer Laurence, Melchior Maria, Vuillermoz Cécile, Rouquette Alexandra
Université Paris-Saclay, Inserm, Université Versailles Saint-Quentin (UVSQ), Centre d'Epidémiologie et de Santé Publique (CESP), Paris, France.
Social Epidemiology Research Team, Institut Pierre Louis d'Epidémiologie Et de Santé Publique (IPLESP), Université, InsermParis, Sorbonne, France.
Soc Psychiatry Psychiatr Epidemiol. 2025 Jun 23. doi: 10.1007/s00127-025-02951-y.
Disparities in mental health across sexual orientation groups and among young adults have long been discussed. The aim of this cross-sectional study was to investigate the moderating effects of sexual orientation on the associations between social factors and depressive symptoms as well as suicidal ideation in young adults.
The study included 6,337 participants aged 18-25y in 2022 from the French EpiCov cohort. The outcome variables were depressive symptoms and suicidal ideation. Poisson regressions with robust error variance were performed to investigate the associations between social factors and outcomes according to sexual orientation (lesbian, gay, bisexual, other, or not defining themselves according to their sexuality: sexual minority (SM); heterosexual or not wishing to answer: Not belonging to SM (NSM)).
The prevalence of depressive symptoms and suicidal ideation was higher in the SM than in the NSM group. Regarding depressive symptoms, significant moderating effects of sexual orientation were observed for female vs male sex (NSM: adjusted Prevalence Ratio (aPR) 1.58[1.28-1.95], SM: aPR 1.03[0.78-1.36]) and age category 22-25y vs 18-21y (NSM: aPR 1.32[1.05-1.67], SM: aPR 0.78[0.59-1.03]). Regarding suicidal ideation, significant moderating effect was observed for not being vs being in a relationship (NSM: aPR 1.55[1.14-2.12], SM: aPR 0.82[0.59-1.13]).
In this study conducted in 2022, well-known social risk factors of mental problems do not explain the higher prevalence of depressive symptoms and suicidal ideation among young SM group. Further studies are needed to understand the specific challenges faced by these young people.
长期以来,人们一直在讨论不同性取向群体以及年轻人之间心理健康方面的差异。这项横断面研究的目的是调查性取向对年轻人社会因素与抑郁症状以及自杀意念之间关联的调节作用。
该研究纳入了2022年来自法国EpiCov队列的6337名18 - 25岁的参与者。结果变量为抑郁症状和自杀意念。采用具有稳健误差方差的泊松回归,根据性取向(女同性恋、男同性恋、双性恋、其他,或不根据其性取向定义自己:性少数群体(SM);异性恋或不愿回答:不属于SM(NSM))来研究社会因素与结果之间的关联。
SM组中抑郁症状和自杀意念的患病率高于NSM组。关于抑郁症状,在性别方面,女性与男性相比观察到性取向的显著调节作用(NSM:调整后患病率比(aPR)1.58[1.28 - 1.95],SM:aPR 1.03[0.78 - 1.36]);在年龄组方面,22 - 25岁与18 - 21岁相比观察到显著调节作用(NSM:aPR 1.32[1.05 - 1.67],SM:aPR 0.78[0.59 - 1.03])。关于自杀意念,在恋爱状况方面,处于恋爱关系与非恋爱关系相比观察到显著调节作用(NSM:aPR 1.55[1.14 - 2.12],SM:aPR 0.82[0.59 - 1.13])。
在2022年进行的这项研究中,众所周知的心理问题社会风险因素并不能解释年轻SM组中抑郁症状和自杀意念的较高患病率。需要进一步研究以了解这些年轻人面临的具体挑战。