Adrovic Ilda, Coenen Michaela, Simmel Stefan, Kus Sandra
Institute for Medical Information Processing, Biometry, and Epidemiology-IBE, Chair of Public Health and Health Services Research, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Elisabeth-Winterhalter-Weg 6, 81377, Munich, Germany.
Pettenkofer School of Public Health, Munich, Germany.
J Occup Rehabil. 2025 Jun 23. doi: 10.1007/s10926-025-10304-4.
This study aims to analyze change over time in health-related quality of life and the current overall health status of patients with severe musculoskeletal injuries, specifically focusing on those who have undergone inpatient rehabilitation following work-related injuries.
Data were sourced from the icfPROreha research project (DRKS-ID: DRKS00014857), involving a multicenter longitudinal study conducted across ten German clinics. The study population comprised patients who had sustained severe musculoskeletal work-related injuries. The EuroQol 5 Dimensions 5 Levels (EQ-5D-5L) was used to assess changes in health-related quality of life (HRQoL) measured at admission (t1), discharge (t2), and four follow-up periods up to 78 weeks after discharge. Descriptive analyses were conducted to illustrate the development of HRQoL across all time points. In addition, the current overall health status was measured using the EuroQol Visual Analogue Scale (EQ-VAS) at the same time points. Multilevel growth models were used to analyze change over time in EQ-VAS scores, considering the biopsychosocial perspective of health as indicated by the International Classification of Functioning, Disability, and Health (ICF), developed by the WHO.
In total, 698 patients [males: 75.2%; mean age 47.5 years (SD ± 12.3)] with severe musculoskeletal work-related injuries were included in the analyses. The mean EQ-VAS at baseline was 50.3 and the mean EQ-5D-5L index was 0.6. Descriptive analyses of the EQ-5D-5L showed significant improvements across all five dimensions of HRQoL after discharge, with the most pronounced changes observed in mobility and usual activities. Moreover, the study demonstrated a significant improvement in the EQ-VAS over time. Baseline EQ-VAS had a substantial influence on subsequent changes, with various factors such as psychological well-being, visible consequences and severity of injury affecting recovery outcomes. Notably, differences in health status over time were observed across different injury types.
The study demonstrates significant enhancements in the current overall health status among patients with traumatic musculoskeletal injuries following workplace or commuting accidents during inpatient rehabilitation. Furthermore, these findings emphasize the application of the ICF framework in capturing the multidimensional aspects of patient recovery. Despite improvements, patients' health status did not reach the levels observed in the general population, indicating the need for ongoing support and targeted interventions to ensure long-term recovery.
本研究旨在分析严重肌肉骨骼损伤患者与健康相关的生活质量随时间的变化以及当前的整体健康状况,特别关注那些因工伤接受住院康复治疗的患者。
数据来源于icfPROreha研究项目(DRKS-ID:DRKS00014857),该项目涉及在德国十家诊所进行的多中心纵向研究。研究人群包括遭受严重肌肉骨骼工伤的患者。使用欧洲五维健康量表5级(EQ-5D-5L)评估在入院时(t1)、出院时(t2)以及出院后长达78周的四个随访期所测量的与健康相关的生活质量(HRQoL)的变化。进行描述性分析以说明所有时间点HRQoL的发展情况。此外,在相同时间点使用欧洲五维健康量表视觉模拟量表(EQ-VAS)测量当前的整体健康状况。考虑到世界卫生组织制定的《国际功能、残疾和健康分类》(ICF)所表明的健康的生物心理社会视角,使用多级增长模型分析EQ-VAS评分随时间的变化。
共有698例严重肌肉骨骼工伤患者[男性:75.2%;平均年龄47.5岁(标准差±12.3)]纳入分析。基线时的平均EQ-VAS为50.3,平均EQ-5D-5L指数为0.6。EQ-5D-5L的描述性分析显示出院后HRQoL的所有五个维度均有显著改善,其中在 mobility和日常活动方面观察到最明显的变化。此外,研究表明EQ-VAS随时间有显著改善。基线EQ-VAS对随后的变化有重大影响,心理健康、可见后果和损伤严重程度等各种因素会影响康复结果。值得注意的是,不同损伤类型在健康状况随时间的变化方面存在差异。
该研究表明,在住院康复期间,因工作场所或通勤事故导致创伤性肌肉骨骼损伤的患者当前的整体健康状况有显著改善。此外,这些发现强调了ICF框架在捕捉患者康复多维度方面的应用。尽管有所改善,但患者的健康状况未达到一般人群所观察到的水平,这表明需要持续的支持和有针对性的干预措施以确保长期康复。