Lainson R, Shaw J J
J Trop Med Hyg. 1977 Feb;80(2):29-35.
Cross-immunity trials in monkeys (Cebus apella apella) and observations on experimental and natural infections in man confirm the separate identity of L. mexicana mexicana, L. m. amazonensis, L. b. braziliensis, L. b. guyanensis and L. b. panamensis. Neither L. m. mexicana nor L. m. amazonensis infections gave protection against subsequent challenge with parasites of the L. braziliensis complex; but recovery from infection with subspecies of L. braziliensis in most cases gave firm resistance to infection with the mexicana parasites. The failure of certain New World leishmanias to immunize against each other has an important bearing on taxonomy, future attempts to prepare vaccines against Leishmania, epidemiology and diagnosis.
对猴子（僧帽猴）进行的交叉免疫试验以及对人类实验性感染和自然感染的观察证实，墨西哥利什曼原虫墨西哥亚种、墨西哥利什曼原虫亚马逊亚种、巴西利什曼原虫巴西亚种、巴西利什曼原虫圭亚那亚种和巴西利什曼原虫巴拿马亚种具有各自独立的特性。墨西哥利什曼原虫墨西哥亚种和墨西哥利什曼原虫亚马逊亚种感染均不能使机体对随后巴西利什曼原虫复合体寄生虫的攻击产生保护作用；但在大多数情况下，从巴西利什曼原虫亚种感染中恢复后，机体对墨西哥利什曼原虫寄生虫感染具有较强的抵抗力。某些新大陆利什曼原虫之间不能相互免疫，这对分类学、未来制备利什曼原虫疫苗的尝试、流行病学和诊断具有重要影响。
