重新审视人类大脑中的兴奋/抑制平衡。 - Suppr

Suppr

超能文献

Rethinking excitation/inhibition balance in the human brain.

作者信息

Cohen Kadosh Roi

机构信息

School of Psychology, University of Surrey, Guildford, UK.

出版信息

Nat Rev Neurosci. 2025 Jun 23. doi: 10.1038/s41583-025-00943-0.

DOI:10.1038/s41583-025-00943-0

PMID:40551004

Abstract

摘要

相似文献

Rethinking excitation/inhibition balance in the human brain.

Nat Rev Neurosci. 2025 Jun 23. doi: 10.1038/s41583-025-00943-0.

Experimental increase of blood glucose alters resting state EEG measures of excitation-inhibition balance.

Exp Physiol. 2021 Apr;106(4):803-811. doi: 10.1113/EP089211. Epub 2021 Feb 27.

Neural excitation/inhibition imbalance and neurodevelopmental pathology in human copy number variant syndromes: a systematic review.

J Neurodev Disord. 2025 Jun 9;17(1):31. doi: 10.1186/s11689-025-09614-8.

Oxytocin ameliorates cognitive impairments by attenuating excitation/inhibition imbalance of neurotransmitters acting on parvalbumin interneurons in a mouse model of sepsis-associated encephalopathy.

J Biomed Res. 2024 May 25;39(2):1-14. doi: 10.7555/JBR.37.20230318.

Aperiodic slope reflects glutamatergic tone in the human brain.

bioRxiv. 2025 May 20:2025.05.15.654118. doi: 10.1101/2025.05.15.654118.

Excitation-inhibition balance abnormally shapes structure-function coupling of gray matter in Parkinson's disease.

NPJ Parkinsons Dis. 2025 Jun 13;11(1):168. doi: 10.1038/s41531-025-01028-6.

Decreased spinal inhibition leads to undiversified locomotor patterns.

Biol Cybern. 2025 Jun 4;119(2-3):12. doi: 10.1007/s00422-025-01011-7.

Identification of neurotransmitter imbalances in the cingulate cortex of NMOSD patients using magnetic resonance spectroscopy.

Cereb Cortex. 2024 Jul 3;34(7). doi: 10.1093/cercor/bhae304.

The role of neuroinflammation in PV interneuron impairments in brain networks; implications for cognitive disorders.

Rev Neurosci. 2025 Jan 24. doi: 10.1515/revneuro-2024-0153.

Adolescent alcohol exposure promotes mechanical allodynia and alters synaptic function at inputs from the basolateral amygdala to the prelimbic cortex.

Elife. 2025 May 8;13:RP101667. doi: 10.7554/eLife.101667.

本文引用的文献

Aperiodic and periodic components of oscillatory brain activity in relation to cognition and symptoms in pediatric ADHD.

Cereb Cortex. 2024 Jun 4;34(6). doi: 10.1093/cercor/bhae236.

Aperiodic EEG and 7T MRSI evidence for maturation of E/I balance supporting the development of working memory through adolescence.

Dev Cogn Neurosci. 2024 Apr;66:101373. doi: 10.1016/j.dcn.2024.101373. Epub 2024 Apr 3.

Plasticity-stability dynamics during post-training processing of learning.

Trends Cogn Sci. 2024 Jan;28(1):72-83. doi: 10.1016/j.tics.2023.09.002. Epub 2023 Oct 17.

Human neuronal excitation/inhibition balance explains and predicts neurostimulation induced learning benefits.

PLoS Biol. 2023 Aug 31;21(8):e3002193. doi: 10.1371/journal.pbio.3002193. eCollection 2023 Aug.

From mechanisms to markers: novel noninvasive EEG proxy markers of the neural excitation and inhibition system in humans.

Transl Psychiatry. 2022 Nov 8;12(1):467. doi: 10.1038/s41398-022-02218-z.

Predicting Math Ability Using Working Memory, Number Sense, and Neurophysiology in Children and Adults.

Brain Sci. 2022 Apr 26;12(5):550. doi: 10.3390/brainsci12050550.

Predicting learning and achievement using GABA and glutamate concentrations in human development.

PLoS Biol. 2021 Jul 22;19(7):e3001325. doi: 10.1371/journal.pbio.3001325. eCollection 2021 Jul.

Precision Medicine Care in ADHD: The Case for Neural Excitation and Inhibition.

Brain Sci. 2021 Jan 13;11(1):91. doi: 10.3390/brainsci11010091.

Parameterizing neural power spectra into periodic and aperiodic components.

Nat Neurosci. 2020 Dec;23(12):1655-1665. doi: 10.1038/s41593-020-00744-x. Epub 2020 Nov 23.

Critical period plasticity in local cortical circuits.

Nat Rev Neurosci. 2005 Nov;6(11):877-88. doi: 10.1038/nrn1787.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Rethinking excitation/inhibition balance in the human brain.

作者信息

Cohen Kadosh Roi

机构信息

School of Psychology, University of Surrey, Guildford, UK.

出版信息

Nat Rev Neurosci. 2025 Jun 23. doi: 10.1038/s41583-025-00943-0.

DOI:10.1038/s41583-025-00943-0

PMID:40551004

Abstract

摘要

相似文献

Rethinking excitation/inhibition balance in the human brain.

Nat Rev Neurosci. 2025 Jun 23. doi: 10.1038/s41583-025-00943-0.

Experimental increase of blood glucose alters resting state EEG measures of excitation-inhibition balance.

Exp Physiol. 2021 Apr;106(4):803-811. doi: 10.1113/EP089211. Epub 2021 Feb 27.

Neural excitation/inhibition imbalance and neurodevelopmental pathology in human copy number variant syndromes: a systematic review.

J Neurodev Disord. 2025 Jun 9;17(1):31. doi: 10.1186/s11689-025-09614-8.

Oxytocin ameliorates cognitive impairments by attenuating excitation/inhibition imbalance of neurotransmitters acting on parvalbumin interneurons in a mouse model of sepsis-associated encephalopathy.

J Biomed Res. 2024 May 25;39(2):1-14. doi: 10.7555/JBR.37.20230318.

Aperiodic slope reflects glutamatergic tone in the human brain.

bioRxiv. 2025 May 20:2025.05.15.654118. doi: 10.1101/2025.05.15.654118.

Excitation-inhibition balance abnormally shapes structure-function coupling of gray matter in Parkinson's disease.

NPJ Parkinsons Dis. 2025 Jun 13;11(1):168. doi: 10.1038/s41531-025-01028-6.

Decreased spinal inhibition leads to undiversified locomotor patterns.

Biol Cybern. 2025 Jun 4;119(2-3):12. doi: 10.1007/s00422-025-01011-7.

Identification of neurotransmitter imbalances in the cingulate cortex of NMOSD patients using magnetic resonance spectroscopy.

Cereb Cortex. 2024 Jul 3;34(7). doi: 10.1093/cercor/bhae304.

The role of neuroinflammation in PV interneuron impairments in brain networks; implications for cognitive disorders.

Rev Neurosci. 2025 Jan 24. doi: 10.1515/revneuro-2024-0153.

Adolescent alcohol exposure promotes mechanical allodynia and alters synaptic function at inputs from the basolateral amygdala to the prelimbic cortex.

Elife. 2025 May 8;13:RP101667. doi: 10.7554/eLife.101667.

本文引用的文献

Aperiodic and periodic components of oscillatory brain activity in relation to cognition and symptoms in pediatric ADHD.

Cereb Cortex. 2024 Jun 4;34(6). doi: 10.1093/cercor/bhae236.

Aperiodic EEG and 7T MRSI evidence for maturation of E/I balance supporting the development of working memory through adolescence.

Dev Cogn Neurosci. 2024 Apr;66:101373. doi: 10.1016/j.dcn.2024.101373. Epub 2024 Apr 3.

Plasticity-stability dynamics during post-training processing of learning.

Trends Cogn Sci. 2024 Jan;28(1):72-83. doi: 10.1016/j.tics.2023.09.002. Epub 2023 Oct 17.

Human neuronal excitation/inhibition balance explains and predicts neurostimulation induced learning benefits.

PLoS Biol. 2023 Aug 31;21(8):e3002193. doi: 10.1371/journal.pbio.3002193. eCollection 2023 Aug.

From mechanisms to markers: novel noninvasive EEG proxy markers of the neural excitation and inhibition system in humans.

Transl Psychiatry. 2022 Nov 8;12(1):467. doi: 10.1038/s41398-022-02218-z.

Predicting Math Ability Using Working Memory, Number Sense, and Neurophysiology in Children and Adults.

Brain Sci. 2022 Apr 26;12(5):550. doi: 10.3390/brainsci12050550.

Predicting learning and achievement using GABA and glutamate concentrations in human development.

PLoS Biol. 2021 Jul 22;19(7):e3001325. doi: 10.1371/journal.pbio.3001325. eCollection 2021 Jul.

Precision Medicine Care in ADHD: The Case for Neural Excitation and Inhibition.

Brain Sci. 2021 Jan 13;11(1):91. doi: 10.3390/brainsci11010091.

Parameterizing neural power spectra into periodic and aperiodic components.

Nat Neurosci. 2020 Dec;23(12):1655-1665. doi: 10.1038/s41593-020-00744-x. Epub 2020 Nov 23.

Critical period plasticity in local cortical circuits.

Nat Rev Neurosci. 2005 Nov;6(11):877-88. doi: 10.1038/nrn1787.