Stoffel Cristhopher, Peixoto Honório Octávio Cuadro, Santos Felipe Kowaleski Dos, Licks Pedro Afonso Keller, Reis Fernando Baldy Dos, Salles Mauro José Costa
Instituto de Ortopedia e Traumatologia, Hospital São Vicente de Paulo, Passo Fundo, RS, Brazil.
Department of Orthopedics and Traumatology, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil.
Rev Bras Ortop (Sao Paulo). 2025 Jun 23;60(2):1-7. doi: 10.1055/s-0045-1809337. eCollection 2025 Apr.
To compare the microbial retrieval rates and the organism types on the surface of stainless-steel pins (SSPs) and hydroxyapatite-coated pins (HCPs) from external fixators (EFs).
The present prospective, non-randomized, multicenter, comparative interventional cohort study occurred from April 2018 to October 2021. The sample consisted of 44 patients with EFs, including 33 with SSPs and 11 with HCPs. We collected two pins from each patient, the one with the best and the one with the worst clinical appearance according to the Maz-Oxford-Nuffield (MON) classification, in an aseptic manner, and sent them for microbiological analysis.
The overall superficial infection (SI) rate was 52.3% (23 of 44 patients), affecting 45.5% (5 of 11) patients with HCPs and 54.5% (18 of 33) patients with SSPs ( = 0.732). Of the 88 pins, 43.2% (38 of 88 pins) yielded microbial identification, with 42 pathogens isolated. was the most frequent organism, accounting for 59.5% (25 of 42 pathogens) of the positive samples. In the best-looking pins, the microbial retrieval rate was significantly lower in HCPs than SSPs, with 18.2% (2 pathogens in 11 pins) and 45.5% (15 pathogens in 33 pins), respectively ( = 0.036). In the worst-looking pins, the microbial retrieval rate in HCPs and SSPs was 27.3% (3 pathogens in 11 pins) and 54.5% (18 pathogens in 33 pins), respectively ( = 0.036).
Microbial retrieval rates were lower in HCPs than in SSPs. However, these differences did not impact clinical infection rates, which were similar in both groups.
比较外固定架上不锈钢针（SSP）和羟基磷灰石涂层针（HCP）表面的微生物检出率及微生物种类。
本前瞻性、非随机、多中心、比较性干预队列研究于2018年4月至2021年10月进行。样本包括44例使用外固定架的患者，其中33例使用SSP，11例使用HCP。我们从每位患者身上无菌采集两枚针，一枚根据马兹 - 牛津 - 纳菲尔德（MON）分类外观最佳，另一枚外观最差，然后将其送去进行微生物分析。
总体浅表感染（SI）率为52.3%（44例患者中的23例），其中使用HCP的患者中有45.5%（11例中的5例）感染，使用SSP的患者中有54.5%（33例中的18例）感染（P = 0.732）。在88枚针中，43.2%（88枚针中的38枚）获得微生物鉴定，共分离出42种病原体。金黄色葡萄球菌是最常见的微生物，占阳性样本的59.5%（42种病原体中的25种）。在外观最佳的针中，HCP的微生物检出率显著低于SSP，分别为18.2%（11枚针中的2种病原体）和45.5%（33枚针中的15种病原体）（P = 0.036）。在外观最差的针中，HCP和SSP的微生物检出率分别为27.3%（11枚针中的3种病原体）和54.5%（33枚针中的18种病原体）（P = 0.036）。
HCP的微生物检出率低于SSP。然而，这些差异并未影响临床感染率，两组临床感染率相似。
