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泪腺多形性腺瘤恶变伴颅内侵犯

Carcinoma Ex-Pleomorphic Adenoma of the Lacrimal Gland with Intracranial Extension.

作者信息

Sharbel Daniel, Atekha Osayamen, Rahimi Scott, Byrd James Kenneth

机构信息

Department of Otolaryngology-Head and Neck Surgery, Medical College of Georgia at Augusta University, Augusta, Georgia, United States.

Medical College of Georgia at Augusta University, Augusta, Georgia, United States.

出版信息

J Neurol Surg Rep. 2025 Jun 23;86(2):e133-e135. doi: 10.1055/a-2629-9251. eCollection 2025 Apr.

DOI:10.1055/a-2629-9251
PMID:40552095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12185180/
Abstract

Carcinoma ex-pleomorphic adenoma (CXPA) of the lacrimal gland is rare, and its management can be complex given its anatomic location. In this case report, we describe our approach to multidisciplinary management of a CXPA with intracranial extension.

摘要

泪腺多形性腺瘤恶变（CXPA）较为罕见，鉴于其解剖位置，其治疗可能较为复杂。在本病例报告中，我们描述了对一例伴有颅内侵犯的CXPA进行多学科治疗的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb35/12185180/1e65697e771d/10-1055-a-2629-9251_26314063.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb35/12185180/cb299d490b66/10-1055-a-2629-9251_26314062.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb35/12185180/1e65697e771d/10-1055-a-2629-9251_26314063.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb35/12185180/cb299d490b66/10-1055-a-2629-9251_26314062.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb35/12185180/1e65697e771d/10-1055-a-2629-9251_26314063.jpg

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本文引用的文献

1
Incidence, clinical features, and survival outcomes of primary malignant lacrimal gland tumors: A population-based analysis.原发性泪腺恶性肿瘤的发病率、临床特征和生存结局：一项基于人群的分析。
Cancer Med. 2024 Feb;13(3):e6831. doi: 10.1002/cam4.6831. Epub 2024 Jan 17.
2
Lacrimal Carcinoma Ex Pleomorphic Adenoma: A Population-based Study.泪腺多形性腺瘤恶变：一项基于人群的研究。
Clin Oncol (R Coll Radiol). 2023 Jan;35(1):65-67. doi: 10.1016/j.clon.2022.10.011. Epub 2022 Nov 1.
3
Perioperative Hypercoagulability in Free Flap Reconstructions Performed for Intracranial Tumors.
颅内肿瘤游离皮瓣重建术中的围手术期高凝状态
Laryngoscope. 2023 May;133(5):1103-1109. doi: 10.1002/lary.30417. Epub 2022 Oct 5.
4
Masses of the Lacrimal Gland: Evaluation and Treatment.泪腺肿物：评估与治疗
J Neurol Surg B Skull Base. 2021 Feb;82(1):100-106. doi: 10.1055/s-0040-1722700. Epub 2021 Feb 18.
5
Recurrent rearrangements of the PLAG1 and HMGA2 genes in lacrimal gland pleomorphic adenoma and carcinoma ex pleomorphic adenoma.PLAG1 和 HMGA2 基因在泪腺多形性腺瘤和癌在多形性腺瘤中的反复重排。
Acta Ophthalmol. 2018 Nov;96(7):e768-e771. doi: 10.1111/aos.13667. Epub 2018 Feb 13.
6
Eye-sparing multidisciplinary approach for the management of lacrimal gland carcinoma.泪腺腺样囊性癌的保眼多学科治疗方法
Head Neck. 2016 Aug;38(8):1258-62. doi: 10.1002/hed.24433. Epub 2016 Mar 29.
7
PLAG1 alteration in carcinoma ex pleomorphic adenoma: immunohistochemical and fluorescence in situ hybridization studies of 22 cases.多形性腺瘤癌变中PLAG1改变：22例病例的免疫组织化学和荧光原位杂交研究
Head Neck Pathol. 2012 Sep;6(3):328-35. doi: 10.1007/s12105-012-0353-8. Epub 2012 Apr 8.