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健康教育干预对慢性阻塞性肺疾病患者治疗依从性及健康状况的影响:一项随机对照试验。

Effect of health education intervention on treatment adherence and health status in patients with Chronic obstruction pulmonary disease: A random control trial.

作者信息

Trieu Nguyen Thi Thu, Hoai Nguyen Thi Yen, Tung Nguyen Ngoc, Thong Tran Huu, Hien Nguyen Thi Thu

机构信息

Faculty of Nursing, Da Nang University of Medical Technology and Pharmacy, Da Nang city, Vietnam.

Can Tho University of Medicine and Pharmacy, Can Tho city, Vietnam.

出版信息

PLoS One. 2025 Jun 24;20(6):e0325192. doi: 10.1371/journal.pone.0325192. eCollection 2025.

DOI:10.1371/journal.pone.0325192
PMID:40554530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12186925/
Abstract

Adherence to treatment is critical to effective management of COPD and is key to addressing the growing burden of disease. So, this study conducted to evaluate the effectiveness of a health education intervention on treatment adherence behavior of COPD outpatients and identify the level of health status improvement. A random control trial was conducted in 2022 at two respiratory outpatient clinics in Da Nang City, Vietnam. 90 participants were divided into two group, 45 members of the health education group who received 5-times consulting about disease knowledge, training using inhallers, breathing exercises at clinic, then 12-times teleconsultation; and 45 controls who only joined surveys. Treatment adherence and level of health status improvement were assessed as outcomes. At beginning, there was no significant difference between the intervention and control groups regarding compliance, disease severity, and airway obstruction (p > 0.05). After three months of intervention, adherence to inhaled medication in the intervention group was 3.2 times higher than in the control group, with statistical significance (p = 0.002, OR=3.2; 95% CI: 1.8-5.3). Similarly, adherence to breathing exercises was 2.5 times greater in the intervention group compared to the control group, with a statistically significant result (p = 0.000, OR=2.5; 95% CI: 1.8-3.4). Overall adherence to treatment was 2.2 times higher in the intervention group than in the control group, also showing statistical significance (p = 0.001, OR=2.2; 95% CI: 1.7-3.1). Additionally, the intervention group demonstrated significant improvements in disease severity and airway obstruction (p < 0.001). Education interventions showed effectiveness in increasing treatment adherence and health status of COPD outpatients. Therefore, a broader program should be conducted in the future.

摘要

坚持治疗对于慢性阻塞性肺疾病(COPD)的有效管理至关重要,也是应对日益加重的疾病负担的关键。因此,本研究旨在评估健康教育干预对COPD门诊患者治疗依从行为的有效性,并确定健康状况改善的程度。2022年在越南岘港市的两家呼吸门诊进行了一项随机对照试验。90名参与者被分为两组,45名健康教育组成员接受了5次疾病知识咨询、在诊所使用吸入器的培训、呼吸练习,然后进行了12次远程咨询;45名对照组参与者仅参加了调查。将治疗依从性和健康状况改善程度作为评估结果。开始时,干预组和对照组在依从性、疾病严重程度和气道阻塞方面无显著差异(p>0.05)。干预三个月后,干预组吸入药物的依从性比对照组高3.2倍,具有统计学意义(p=0.002,OR=3.2;95%CI:1.8-5.3)。同样,干预组呼吸练习的依从性比对照组高2.5倍,结果具有统计学意义(p=0.000,OR=2.5;95%CI:1.8-3.4)。干预组的总体治疗依从性比对照组高2.2倍,也具有统计学意义(p=0.001,OR=2.2;95%CI:1.7-3.1)。此外,干预组的疾病严重程度和气道阻塞有显著改善(p<0.001)。教育干预在提高COPD门诊患者的治疗依从性和健康状况方面显示出有效性。因此,未来应开展更广泛的项目。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4464/12186925/064b54e4da1d/pone.0325192.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4464/12186925/064b54e4da1d/pone.0325192.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4464/12186925/064b54e4da1d/pone.0325192.g001.jpg

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