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遗传性白内障大鼠的血清脂质过氧化物水平。

Serum lipid peroxide levels in rats with inherited cataracts.

作者信息

Yagi K, Komura S, Ihara N, Abe H, Konishi H, Arichi S

出版信息

J Appl Biochem. 1985 Jun;7(3):202-6.

PMID:4055555
Abstract

In a new strain of rat with inherited cataracts, a postnatal increase in serum lipid peroxide level was observed. It reached the maximum on the 13th day after birth. This seems to be a reflection of the increased lipid peroxides in the liver. In accordance with the increase in serum lipid peroxide level, the occurrence of vacuoles in the subcapsular fibers of the posterior region of the lens was observed by electron microscopy, suggesting a relationship between the increase in serum lipid peroxides and the provocation of cataract formation.

摘要

在一种患有遗传性白内障的新型大鼠品系中,观察到出生后血清脂质过氧化物水平升高。在出生后第13天达到最高值。这似乎反映了肝脏中脂质过氧化物的增加。与血清脂质过氧化物水平的升高相一致,通过电子显微镜观察到晶状体后部区域囊下纤维中出现空泡,提示血清脂质过氧化物的增加与白内障形成的诱发之间存在关联。

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Serum lipid peroxide levels in rats with inherited cataracts.遗传性白内障大鼠的血清脂质过氧化物水平。
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Microtubules in experimental cataracts: disappearance of microtubules of epithelial cells and lens fibers in colchicine-induced cataracts.实验性白内障中的微管:秋水仙碱诱导的白内障中上皮细胞和晶状体纤维微管的消失
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Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats.大鼠中毒性肝炎时谷胱甘肽过氧化物酶和谷胱甘肽还原酶的表达及自由基过程水平
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3
Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat.
染料木黄酮和含有染料木黄酮的膳食补充剂可加速雄性 ICR/f 大鼠白内障形成的早期阶段。
Exp Eye Res. 2011 Feb;92(2):120-7. doi: 10.1016/j.exer.2010.12.006. Epub 2010 Dec 10.
4
Tissue localization and solubilities of αA-crystallin and its numerous C-terminal truncation products in pre- and postcataractous ICR/f rat lenses.αA-晶体蛋白及其众多C末端截短产物在白内障前和白内障后ICR/f大鼠晶状体中的组织定位和溶解性
Invest Ophthalmol Vis Sci. 2010 Oct;51(10):5153-61. doi: 10.1167/iovs.10-5302. Epub 2010 Apr 30.