Shimoji Yuko, Mekaru Keiko, Ikemura Akiko, Tamashiro Natsuki, Chinen Shuko, Nakamura Rie, Heshiki Chiaki, Kudaka Wataru, Sekine Masayuki
Department of Obstetrics and Gynecology, Graduate School of Medicine University of the Ryukyus Nishihara Japan.
Reprod Med Biol. 2025 Jun 24;24(1):e12665. doi: 10.1002/rmb2.12665. eCollection 2025 Jan-Dec.
Ovarian transposition (OT) is performed to preserve ovarian function in patients undergoing pelvic or abdominal radiotherapy. Although complications, such as ovarian torsion and cyst formation, have been reported, ovulation-related peritoneal irritation requiring surgical intervention after pediatric OT has not been documented. In this case, a 12-year-old girl who underwent bilateral OT at the age of 6 years during treatment for recurrent rhabdomyosarcoma presented with severe pain in the right lower quadrant. Owing to prior pelvic radiotherapy, the assessment of menstrual history was unreliable. Considering the young age of the patient and the absence of a definitive diagnosis, hormonal therapy, such as low-dose estrogen-progestin therapy, was withheld. Conservative management with analgesics was initiated; however, the pain persisted and progressively worsened.
Emergent laparoscopic OT release was performed for diagnostic and therapeutic purposes, owing to the severity of pain. Intraoperative findings revealed corpus luteum in the retracted right ovary. Postoperatively, the patient's symptoms resolved immediately without recurrence.
Ovulation-induced peritoneal irritation should be recognized as a potential postoperative complication following childhood OT. In adolescent patients with a history of pediatric OT and pelvic radiotherapy, ovulation-related complications should be carefully considered during the differential diagnosis of acute abdominal pain.
卵巢移位术(OT)用于在接受盆腔或腹部放疗的患者中保留卵巢功能。尽管已报道了诸如卵巢扭转和囊肿形成等并发症,但小儿OT术后需要手术干预的与排卵相关的腹膜刺激尚未见文献记载。在此病例中,一名12岁女孩在6岁时因复发性横纹肌肉瘤接受治疗期间接受了双侧OT,现出现右下腹剧痛。由于既往盆腔放疗,月经史评估不可靠。考虑到患者年龄小且未明确诊断,暂未给予低剂量雌激素 - 孕激素疗法等激素治疗。开始使用镇痛药进行保守治疗;然而,疼痛持续且逐渐加重。
由于疼痛严重,为诊断和治疗目的进行了急诊腹腔镜OT松解术。术中发现回缩的右卵巢中有黄体。术后,患者症状立即缓解,未复发。
排卵引起的腹膜刺激应被视为小儿OT术后的潜在并发症。在有小儿OT和盆腔放疗史的青少年患者中,急性腹痛的鉴别诊断时应仔细考虑与排卵相关的并发症。