Willms B
MMW Munch Med Wochenschr. 1977 Apr 15;119(15):513-6.
The treatment of diabetes may be improved by a more physiological insulin supply and by supplements to the insulin supply. Grafting the entire pancreas or transplantation of the islet cells represents an improvement in the insulin supply. But because fo the lack of donor material and immunological difficulties, the realization of these two methods may be questionable. On the other hand the implantation of an artificial B cell seeems realizable in the foreseeable future. Such a method would be indicated in a diabetic whose life is threatened by late complications. Somatostatin is available as a supplement to insulin therapy because it eliminates the growth hormone as possible source of diabetic vascular complications and it blocks the secretion of hormones with a contrainsular effect.
通过更符合生理需求的胰岛素供应以及胰岛素供应的补充剂，糖尿病的治疗可能会得到改善。移植整个胰腺或胰岛细胞移植代表了胰岛素供应方面的一种改进。但由于缺乏供体材料以及存在免疫方面的困难，这两种方法的实现可能存在问题。另一方面，在可预见的未来，植入人工B细胞似乎是可行的。这种方法适用于因晚期并发症而生命受到威胁的糖尿病患者。生长抑素可作为胰岛素治疗的补充剂，因为它消除了生长激素这一糖尿病血管并发症的可能来源，并且它能阻断具有抗胰岛作用的激素的分泌。
