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一名儿童以眼眶蜂窝织炎为表现的不完全川崎病

Incomplete Kawasaki Disease Presenting as Orbital Cellulitis in a Child.

作者信息

Rabbani Mohammed, Kumar K Jagadish, Manjunath V G, Nandish H R

机构信息

Department of Pediatrics, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.

出版信息

J Curr Ophthalmol. 2025 Jun 5;36(3):307-309. doi: 10.4103/joco.joco_111_24. eCollection 2024 Jul-Sep.

Abstract

PURPOSE

To describe a case of periorbital cellulitis as the manifestation of Kawasaki disease (KD).

METHODS

A single case report.

RESULTS

A 15-month-old child presented with fever and swelling around the eyes, initially diagnosed as orbital cellulitis. On examination, the child exhibited bilateral orbital swelling with conjunctival congestion, strawberry tongue, cracked lips, significant bilateral cervical lymphadenopathy, and perianal excoriation. Although many clinical features were compatible with KD, the diagnostic criteria for KD were not fully met. Despite 48 h of antibiotic therapy, the child continued to experience high-grade fever spikes. Consequently, the diagnosis was reviewed and reclassified as incomplete KD. The child was then administered intravenous immunoglobulin (IVIG) at a dosage of 2 g/kg over 10 h. Within 48 h of IVIG administration, the fever subsided and the periorbital swelling decreased.

CONCLUSIONS

The diagnosis of incomplete KD requires a high index of suspicion as the delay in diagnosis may lead to coronary involvement. Any young child with orbital cellulitis unresponsive to antibiotic therapy should be investigated for underlying KD.

摘要

目的

描述1例以眶周蜂窝织炎为表现的川崎病(KD)病例。

方法

单病例报告。

结果

一名15个月大的儿童出现发热及眼周肿胀,最初被诊断为眼眶蜂窝织炎。检查发现,该患儿双侧眼眶肿胀,伴有结膜充血、草莓舌、嘴唇干裂、双侧颈部淋巴结明显肿大及肛周皮肤破损。尽管许多临床特征与KD相符,但KD的诊断标准未完全满足。尽管进行了48小时的抗生素治疗,患儿仍持续出现高热峰值。因此,对诊断进行了重新评估并重新分类为不完全KD。随后,患儿接受了静脉注射免疫球蛋白(IVIG)治疗,剂量为2 g/kg,持续10小时。在IVIG给药后48小时内,发热消退,眶周肿胀减轻。

结论

不完全KD的诊断需要高度怀疑,因为诊断延迟可能导致冠状动脉受累。任何对抗生素治疗无反应的眼眶蜂窝织炎幼儿都应排查潜在的KD。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/defd/12184868/366e9c48dbd6/JCO-36-307-g001.jpg

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