The people behind the papers - Anna Philpott and William Beckman.

Achaete-Scute homolog 1 (ASCL1) is a proneural transcriptional regulator that modulates both cell proliferation and differentiation of neuroblasts (immature nerve cells) during development. In their study, Anna Philpott and colleagues show that ASCL1 performs distinct functions related to proliferation or differentiation in neuroblastoma cells in a cell cycle stage-dependent manner. To know more about their work, we spoke to the first author, William Beckman, and the corresponding author, Anna Philpott, Professor of Cancer and Developmental Biology at Cambridge Stem Cell Institute and Head of the School of the Biological Sciences at the University of Cambridge, UK.